I also placed both interferons on cat tongue cells in cell culture and noted antiviral activity for interferon from nasal secretions ... The use of natural bovine interferon beta in cats with naturally occurring cases of feline leukemia ...
Author: Joseph Cummins
Publisher: Simon and Schuster
Touted as a potential breakthrough cancer therapy in the 1980s by the scientific community and publications such as TIME and Newsweek magazine, the reputation of interferon has not lived up to its early promise. Interferons are small proteins with anti-viral and anti-cancer effects, which have the power to modulate the functioning of the immune system. But Dr. Joseph Cummins, an early interferon pioneer, holder of sixteen US medical patents, author of more than sixty scientific publications, as well as having taught veterinary medicine at the University of Missouri, University of Illinois, and Texas A & M University, argues that the current thinking on interferon is fundamentally flawed. Interferon is created in small quantities in the body in response to infection, and seems to work best at these low dosages. However, the public health cowboys, working under the assumption that anything good in tiny amounts must be better in massive amounts, pursued exactly the wrong strategy. High-dose interferon does not work in the body and may even cause problems. The first remarkable results for interferon and the flu were reported by the Soviets in the 1970s, but Western medicine discounted these findings because they believed the dosages were so low they couldn’t possibly be effective. In the 1980s, when interferon was expensive to produce and only small quantities could be manufactured, the results were remarkable. Dr. Cummins was an early pioneer of low-dose interferon, and his remarkable findings among animals led to collaborations with medical doctors for human trials, even going so far as Africa at the height of the HIV-AIDS epidemic. Cummins reviews the evidence for this inexpensive, safe treatment and makes an eloquent argument for medical science to take another look at interferon to tackle today’s most challenging health conditions, including COVID-19.
Author: Kyōto Daigaku. Wirusu KenkyūjoPublish On: 1977
Titration of interferon was carried out as described previously (5) by the method based on the inhibition of viral ... In the case of non-immune induction, interferon is detected at 4 h and reaches maximum at 8-24 h after challenge of ...
Katano M, Yamamoto H, Sato Set al (1987) A case of gastric cancer with multiple liver metastasis responding to a combination therapy of recombinant interferon gamma (KW2202) and 5-FU. Jpn J Cancer Chemother 14, 3351. Kato I, Kimura S, ...
Author: Roumen G. Tsanev
Publisher: CRC Press
Now for the first time, one comprehensive book summarizes and analyzes the numerous scientific papers and reviews covering selected aspects of the structure, biological activities, and clinical effects of immune interferon, also known as interferon-gamma(IFN-gamma). Immune Interferon: Properties and Clinical Applications is essential reading for an
A case of IFN - a - induced akathisia responded well to benztropine . Thyroid dysfunction may require ablation or thyroid hormone replacement , depending upon the nature of the disorder and the responsiveness to discontinuation of IFN ...
Author: Thomas Markham Brown
Publisher: American Psychiatric Pub
Both prescription and non-prescription medications used in medicine and psychiatry can cause a varietyof problems for those taking them, both in terms of their behavior and their ability to think. The first book to thoroughly examine how to recognize and manage the psychological side-effects of these medicines, this exhaustive work also provides a fingertip source of vital information for everyone from psychiatrists, primary care doctors and other medical subspecialty practitioners to students, residents and general readers. Noted physicians Thomas Markham Brown and Alan Stoudemire cover all of the major medications used in medicine and psychiatry, with full chapters on such topics as: * Antipsychotics* Antidepressants* Lithium* Anticonvulsants* Anesthetic agents* Sedative-Hypnotic and related agents* Antibiotics* Cardiovascular agents* Antineoplastic agents* Gastrointestinal agents* Pulmonary agents* Hematologic agents* Antilipemic agents* Drugs affecting the endocrine system Throughout this information-packed reference, the authors, noted physicians Thomas Markham Brown and Alan Stoudemire, cover all of the major medications used in medicine and psychiatry. They focus on the fundamental ways drugs cause cognitive toxicity and map strategies for clinical management. They also address the consequences of drug interactions and the basic pathophysiology of central nervous system toxicity. With the help of Psychiatric Side Effects of Prescription and Over-the-Counter Medications, readers will be able to quickly identify the ways drugs sometimes negatively affect behavior and ability to reason, and then determine the best practical course for treating those problems. A CD-ROM containing the complete contents of Psychiatric Side Effects of Prescription and Over the Counter Medications is included. Fully searchable, this CD-ROM is compatible on both MACINTOSH and WINDOWS systems.
Analysis of Adjuvant Interferon for Melanoma The Eastern Cooperative Oncology Group (ECOG) clinical trial EST1684 compared ... In this case, one month spent with interferon side effects is valued the same as one half month spent in best ...
Author: Mounir Mesbah
Publisher: Springer Science & Business Media
On October 16 and 17, 2000, we hosted an international workshop entitled "Statistical Design, Measurement, and Analysis of Health Related Quality of Life." The workshop was held in the beautiful city of Arradon, South Brittany, France with the main goal of fostering an interdisciplinary forum for discussion of theoretical and applied statistical issues arising in studies of health-related quality of life (HRQoL). Included were biostatisticians, psychometricians and public health professionals (e.g., physicians, sociologists, psychologists) active in the study ofHRQoL. In assembling this volume, we invited each conference participant to contribute a paper based on his or her presentation and the ensuing and very interesting discussions that took place in Arradon. All papers were peer-reviewed, by anonymous reviewers, and revised before final editing and acceptance. Although this process was quite time consuming, we believe that it greatly improved the volume as a whole, making this book a valuable contribution to the field ofHRQoL research. The volume presents a broad spectrum of papers presented at the Workshop, and thus illustrates the range of current research related to the theory, methods and applications of HRQoL, as well as the interdisciplinary nature ofthis work. Following an introduction written by Sir David Cox, it includes 27 articles organized into the following chapters.
... heat denaturation during virus/adventitious agent removal increased product aggregation in the case of urokinase; shear force from product filtration increased product aggregation and so did low pH as shown in the case of interferon ...
Author: Sarfaraz K. Niazi
Publisher: CRC Press
More than 20 billion dollars worth of biopharmaceuticals are scheduled to go off-patent by 2006. Given the strong political impetus and the development of technological tools that can answer the questions regulatory authorities may raise, it is inevitable that the FDA and EMEA will allow biogeneric or biosimilar products. Even with all the regulato
In the case of leukocyte interferon it is not known whether the fever reaction is caused by interferon or by impurities . So far no data are available on the pyrogenicity of completely pure leukocyte interferon .
Kim and colleagues published their study in the Journal of Korean Medical Science (Interferon-Alpha-Induced Destructive Thyroiditis Followed by Graves' Disease in a Patient with Chronic Hepatitis C: A Case Report.
Advances in Interferon Type I Research and Application / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Interferon Type I. The editors have built Advances in Interferon Type I Research and Application / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Interferon Type I in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Interferon Type I Research and Application / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Interferon coupled to antibodies hits its target Clouds over a warmer Britain Transmembrane molecule helps to ... That would not be the case if interferon's ability to stimulate natural killer cells or trigger other agents were the most ...
New Scientist magazine was launched in 1956 "for all those men and women who are interested in scientific discovery, and in its industrial, commercial and social consequences". The brand's mission is no different today - for its consumers, New Scientist reports, explores and interprets the results of human endeavour set in the context of society and culture.
Horikawa N, Yamazaki T, Sagawa M, Nagata T. A case of akathisia during interferon-alpha therapy for chronic hepatitis type C. Gen Hosp Psychiatry. 1999;21(2):134–135. 66. Moulignier A, Allo S, Zittoun R, Gout O. Recombinant ...
Author: Jeffrey K. Aronson
Elsevier now offers a series of derivative works based on the acclaimed Meyler’s Side Effect of Drugs, 15th Edition. These individual volumes are grouped by specialty to benefit the practicing biomedical researcher and/or clinician. There has been significant progress in the development of targeted therapy drugs that act specifically on certain cancers, and that minimize damage to normal cells. Oncologists and cancer researchers will rely on this volume to determine effective drug treatments. The only drug guide that includes clinical case studies and expert analysis UNIQUE! Features not only anticancer drugs, but also all other drugs that act upon related organ systems affected by cancer Most complete cross referencing of drug-drug interactions available Latest content from the most highly regarded compilation of drug side effects: Side Effects of Drugs Annual serial