Dermatology and the New Genetics

Dermatology and the New Genetics

The final section describes antenatal diagnosis, counselling and gene therapy. The theme of this book is to bridge the gap between clinical dermatology and the new genetics.

Author: Celia Moss

Publisher: Wiley-Blackwell

ISBN: 063203582X

Category: Medical

Page: 208

View: 397

Dermatologists, unlike, for instance, haematologists, are not generally trained in high science and tend to be unfamiliar with the language of the "New Genetics". Lacking an interpreter, they can neither understand nor exploit the exciting developments in this field. This two-author volume gives a straight-forward and uniform account of the subject. Relevant and accessible to clinical dermatologists, the text begins with a refresher course in simple background genetics and the development of skin in this context. It goes on, in the two largest sections of the book, to look at the genetics of epidermal and dermal skin disorders; each of these sections is divided into groups of conditions. The final section describes antenatal diagnosis, counselling and gene therapy. The theme of this book is to bridge the gap between clinical dermatology and the new genetics. It provides a straightforward and uniform account of the subject, relevant and accessible to clinical dermatologists, beginning with a refresher course in simple background genetics and the development of skin in this context
Categories: Medical

Harper s Textbook of Pediatric Dermatology

Harper s Textbook of Pediatric Dermatology

This new fourth edition includes: Greater focus on the genetics behind skin disease, including new genes/genodermatoses, progress in genetic analysis, and stem cell transplants Increased coverage of lasers and other technologies used to ...

Author: Peter H. Hoeger

Publisher: John Wiley & Sons

ISBN: 9781119142805

Category: Medical

Page: 2656

View: 710

A consummate classic with a fresh approach to pediatric dermatology Children ́s skin is different. Maturation affects the epidermal barrier, the cutaneous microbiome, adnexal structures, vasculature, and transcutaneous absorption of drugs. The immature skin is more susceptible to pathogens and environmental disruption. Many genetic disorders are either present at birth or manifest early in childhood. Skin diseases thus present differently in children than in adults. Pediatric dermatology has seen significant advances over the last decade, particularly in the field of molecular genetics research, which has furthered our understanding of the pathogenesis of many skin diseases and the development of new approaches to treatment. This fourth edition of the Harper classic provides state-of-the-art information on all aspects of skin disease in children. It covers the diagnosis and treatment of all conditions - both common and rare - with a consistently evidence-based approach. Existing content has been refreshed and fully updated to reflect emerging thinking and to incorporate the latest in research and clinical data - especially at the genetic level. This new fourth edition includes: Greater focus on the genetics behind skin disease, including new genes/genodermatoses, progress in genetic analysis, and stem cell transplants Increased coverage of lasers and other technologies used to treat skin disease More summary tables, learning points, tables of differential diagnosis, and clinical algorithms for diagnosis and management Additional online features, including patient information links and multiple choice questions Harper's Textbook of Pediatric Dermatology delivers crucial clinical insights and up-to-date research information that spans the breadth of the field. As the most comprehensive reference book on this subject available, this revised fourth edition will support and guide the daily practice of both dermatologists and pediatricians across the world.
Categories: Medical

Harper s Textbook of Pediatric Dermatology 2 Volume Set

Harper s Textbook of Pediatric Dermatology  2 Volume Set

This fourth edition of the Harper classic provides state-of-the-art information on all aspects of skin disease in children.

Author: Peter H. Hoeger

Publisher: Wiley-Blackwell

ISBN: 1119142199

Category: Medical

Page: 2656

View: 220

A consummate classic with a fresh approach to pediatric dermatology Children ́s skin is different. Maturation affects the epidermal barrier, the cutaneous microbiome, adnexal structures, vasculature, and transcutaneous absorption of drugs. The immature skin is more susceptible to pathogens and environmental disruption. Many genetic disorders are either present at birth or manifest early in childhood. Skin diseases thus present differently in children than in adults. Pediatric dermatology has seen significant advances over the last decade, particularly in the field of molecular genetics research, which has furthered our understanding of the pathogenesis of many skin diseases and the development of new approaches to treatment. This fourth edition of the Harper classic provides state-of-the-art information on all aspects of skin disease in children. It covers the diagnosis and treatment of all conditions - both common and rare - with a consistently evidence-based approach. Existing content has been refreshed and fully updated to reflect emerging thinking and to incorporate the latest in research and clinical data - especially at the genetic level. This new fourth edition includes: Greater focus on the genetics behind skin disease, including new genes/genodermatoses, progress in genetic analysis, and stem cell transplants Increased coverage of lasers and other technologies used to treat skin disease More summary tables, learning points, tables of differential diagnosis, and clinical algorithms for diagnosis and management Additional online features, including patient information links and multiple choice questions Harper's Textbook of Pediatric Dermatology delivers crucial clinical insights and up-to-date research information that spans the breadth of the field. As the most comprehensive reference book on this subject available, this revised fourth edition will support and guide the daily practice of both dermatologists and pediatricians across the world.
Categories: Medical

Dermatology

Dermatology

The book provides comprehensive information highlighting recent developments in the field of dermatology. Several distinct skin diseases are inherited as Mendelian inheritance.

Author: Deb Willis

Publisher:

ISBN: 1632421070

Category:

Page: 172

View: 487

The book provides comprehensive information highlighting recent developments in the field of dermatology. Several distinct skin diseases are inherited as Mendelian inheritance. The cause of genetic skin disorders is mutations in the genes encoding proteins expressing in skin, melanocytes, skin appendages and immune-related cells. Recognition of genes and explanation of function of the encoded proteins may provide latest techniques to tackle the disorders. The aim of this book is to provide latest information regarding every disorder to physicians, dermatologists and scientists, and offer new therapies to affected individuals.
Categories:

Harper s Textbook of Pediatric Dermatology 2 Volume Set

Harper s Textbook of Pediatric Dermatology  2 Volume Set

The third edition of this highly regarded text continues to provide a comprehensive resource for pediatric dermatologists.

Author: Alan D. Irvine

Publisher: Wiley-Blackwell

ISBN: 1405176954

Category: Medical

Page: 2816

View: 928

The third edition of this highly regarded text continues to provide a comprehensive resource for pediatric dermatologists. The book offers evidence-based diagnosis and treatment recommendations and covers both common and rare conditions, including emerging conditions and research, especially at the genetic level. A refreshing new text design makes the book more accessible, and new editors and contributors bring a distinctly international perspective to the work.
Categories: Medical

Harper s Textbook of Pediatric Dermatology

Harper s Textbook of Pediatric Dermatology

This new fourth edition includes: Greater focus on the genetics behind skin disease, including new genes/genodermatoses, progress in genetic analysis, and stem cell transplants Increased coverage of lasers and other technologies used to ...

Author: Peter H. Hoeger

Publisher: Wiley-Blackwell

ISBN: 1119142814

Category: Pediatric dermatology

Page: 2656

View: 834

A consummate classic with a fresh approach to pediatric dermatology Children ́s skin is different. Maturation affects the epidermal barrier, the cutaneous microbiome, adnexal structures, vasculature, and transcutaneous absorption of drugs. The immature skin is more susceptible to pathogens and environmental disruption. Many genetic disorders are either present at birth or manifest early in childhood. Skin diseases thus present differently in children than in adults. Pediatric dermatology has seen significant advances over the last decade, particularly in the field of molecular genetics research, which has furthered our understanding of the pathogenesis of many skin diseases and the development of new approaches to treatment. This fourth edition of the Harper classic provides state-of-the-art information on all aspects of skin disease in children. It covers the diagnosis and treatment of all conditions - both common and rare - with a consistently evidence-based approach. Existing content has been refreshed and fully updated to reflect emerging thinking and to incorporate the latest in research and clinical data - especially at the genetic level. This new fourth edition includes: Greater focus on the genetics behind skin disease, including new genes/genodermatoses, progress in genetic analysis, and stem cell transplants Increased coverage of lasers and other technologies used to treat skin disease More summary tables, learning points, tables of differential diagnosis, and clinical algorithms for diagnosis and management Additional online features, including patient information links and multiple choice questions Harper's Textbook of Pediatric Dermatology delivers crucial clinical insights and up-to-date research information that spans the breadth of the field. As the most comprehensive reference book on this subject available, this revised fourth edition will support and guide the daily practice of both dermatologists and pediatricians across the world.
Categories: Pediatric dermatology

Harper s Textbook of Pediatric Dermatology 2 Volume Set

Harper s Textbook of Pediatric Dermatology  2 Volume Set

The third edition of this highly regarded text continues to provide a comprehensive resource for pediatric dermatologists.

Author: Prof. Dr. Alan D. Irvine

Publisher: John Wiley & Sons

ISBN: 9781444345377

Category: Medical

Page: 2816

View: 960

The third edition of this highly regarded text continues to provide a comprehensive resource for pediatric dermatologists. The book offers evidence-based diagnosis and treatment recommendations and covers both common and rare conditions, including emerging conditions and research, especially at the genetic level. A refreshing new text design makes the book more accessible, and new editors and contributors bring a distinctly international perspective to the work.
Categories: Medical

Current Genetics in Dermatology

Current Genetics in Dermatology

This book presents current topics in genetics in the dermatologic field. Various skin disorders are inherited as mendelian inheritance.

Author: Naoki Oiso

Publisher: IntechOpen

ISBN: 9535109715

Category: Medical

Page: 170

View: 355

This book presents current topics in genetics in the dermatologic field. Various skin disorders are inherited as mendelian inheritance. Genetic skin disorders are caused by mutations in the genes encoding proteins expressing in skin, skin appendages, melanocytes and immune-associated cells. Identification of genes and elucidation of function of the encoded proteins may provide novel strategies to overcome the disorders. We hope that this book offers sufficient current information in each disorder to scientists, physicians and dermatologists, and that novel therapies will be provided to affected individuals via these chapters.
Categories: Medical

Current Genetics in Dermatology

Current Genetics in Dermatology

This book presents current topics in genetics in the dermatologic field. Various skin disorders are inherited as mendelian inheritance.

Author: Naoki Oiso

Publisher: BoD – Books on Demand

ISBN: 9789535109716

Category: Medical

Page: 170

View: 963

This book presents current topics in genetics in the dermatologic field. Various skin disorders are inherited as mendelian inheritance. Genetic skin disorders are caused by mutations in the genes encoding proteins expressing in skin, skin appendages, melanocytes and immune-associated cells. Identification of genes and elucidation of function of the encoded proteins may provide novel strategies to overcome the disorders. We hope that this book offers sufficient current information in each disorder to scientists, physicians and dermatologists, and that novel therapies will be provided to affected individuals via these chapters.
Categories: Medical

ABC of Dermatology

ABC of Dermatology

ABC of Dermatology is the bestselling, practical guide for anyone involved in clinical dermatology.

Author: Rachael Morris-Jones

Publisher: John Wiley & Sons

ISBN: 9781119488989

Category: Medical

Page: 280

View: 702

ABC of Dermatology is the bestselling, practical guide for anyone involved in clinical dermatology. This fully illustrated book helps readers identify, recognise, treat, and manage the common dermatological conditions encountered in daily practice. The seventh edition has been revised and updated to incorporate current approaches to the management of skin disease, such as the use of new biological agents for treating inflammatory disease and tumours, and new chapters on cosmetic dermatology procedures, genital dermatology and cutting-edge advances in genetics and pathophysiology. Presents a practical approach to clinical dermatology that relates skin changes to specific skin conditions and underlying pathology Summarises relevant pathological processes, diagnostic features, learning points, and treatment options for a range of conditions Offers hundreds of full-colour clinical photographs that illustrate manifestations of skin disease in a multitude of diverse skin tones and ethnic groups Covers a wide range of skin management treatments, from simple interventions to sophisticated immunotherapies Includes insights on the increasing use of teledermatology by remote doctors ABC of Dermatology is a must-have guide for GPs, junior doctors, medical students, and primary healthcare professionals.
Categories: Medical

Genetics of Melanoma

Genetics of Melanoma

This book discusses the molecular, biological, pathological, and clinical aspects of melanoma, with special emphasis in the new concepts of melanoma genetics.

Author: Carlos A. Torres-Cabala

Publisher: Springer

ISBN: 9781493935543

Category: Medical

Page: 288

View: 576

This book discusses the molecular, biological, pathological, and clinical aspects of melanoma, with special emphasis in the new concepts of melanoma genetics. A multidisciplinary group of experts in Genetics, Dermatology, Pathology, and Melanoma Medical Oncology contribute state-of-the-art knowledge in melanoma research and clinical management, not only exposing the current status of knowledge of the topics but also providing their personal experiences and ideas about the future and potential practical application of the genetic aspects of melanoma. During the last few years we have witnessed an impressive amount of discoveries in the field of melanoma genetics which have changed our approach in understanding the pathogenesis and treatment of this lethal disease. Genetics of Melanoma is a practical approach to melanoma genetic mechanisms and their application in the diagnosis and treatment of this malignancy. It is an essential source of updated information and a powerful tool for clinicians, pathologists, and basic scientists who wish to understand, apply, and investigate the multiple new aspects of melanoma genetics.
Categories: Medical

British Journal of Hospital Medicine

British Journal of Hospital Medicine

Impact of the ' new ' new genetics ' on dermatology Figure 1. Scarring epidermolysis bullosa : the nails have been lost . The defect is in type VII collagen ...

Author:

Publisher:

ISBN: NWU:35558003392061

Category:

Page:

View: 727

Categories:

Genetic Diseases of the Skin

Genetic Diseases of the Skin

For both groups this book will be a new and valuable source of help. Spring 1979 F. CLARKE FRASER, Ph.D., M.D.

Author: V. M. Der Kaloustian

Publisher: Springer Science & Business Media

ISBN: 9783642671524

Category: Medical

Page: 342

View: 380

The two organs of the body most accessible to examination are the eye and the skin and its appendages. That is why, it is said, ophthalmological genetics is in such flourishing good health. Dermatological genetics does not seem to have benefited so much from the skin being on the outside, and there are but few dermatological counterparts to the volumes of Sorsby, Waardenburg, Franceschetti and Franr,;ois, among others. But thanks to the growing interest in medical genetics, and the modern sophisticated tech niques of molecular, biochemical, and ultrastructural examination, der matology is beginning to catch up, as the appearance of this volume testifies. Because of the growing body of knowledge and the heightened awareness of genetics by both patients and physicians, dermatologists not only will be asked more often about the inheritance of skin conditions they diagnose but increasingly will have the opportunity to diagnose a variety of inborn errors and syndromes by their dermatologic manifestations. On the other hand, syndromologists, clinical geneticists, and physicians are continually seeing patients with diagnostic clues in the skin that they must be able to appreciate. For both groups this book will be a new and valuable source of help. Spring 1979 F. CLARKE FRASER, Ph.D., M.D.
Categories: Medical

The Ichthyoses

The Ichthyoses

This book will effectively help to establish a correct diagnosis, as a basis for genetic counseling. Dr. Traupe proposes a new classification of the ichthyoses, based on reason able clinical criteria.

Author: Heiko Traupe

Publisher: Springer Science & Business Media

ISBN: 9783642736506

Category: Medical

Page: 253

View: 454

It is a great pleasure for me to see this work in print. As outlined by Dr. Traupe, at least 20 different types of ichthyosis have been identified to date. This book will effectively help to establish a correct diagnosis, as a basis for genetic counseling. Dr. Traupe proposes a new classification of the ichthyoses, based on reason able clinical criteria. He lets the reader share in his enormous knowledge and safely guides him through the difficult field of nomenclature. He describes the particular nature of these scaling disorders in a manner as simple as possible. During the last few years, research on ichthyosis has become a fascinating scientific challenge due to the introduction of novel investigative approaches. The main advantage of this book lies in the fact that the author successfully combines recent achievements made in lipid analysis, enzymology, electron microscopy, and molecular genetics. Heiko Traupe began his career in dermatology 11 years ago, as a resident in the Department of Dermatology in Munster. As we were both interested in the genetic aspects of skin diseases, this was the starting point of a most fruitful collaboration, which is still continuing. During our common work in Munster, Dr. Traupe was able, thanks to his unceasing clinical curiosity, to describe many novel aspects within the field of ichthyosis, and I took pride in coauthoring papers on new items such as cryptorchidism as a fea ture associated with X-linked recessive ichthyosis, autosomal dominant lamellar ichthyosis, and alopecia ichthyotica.
Categories: Medical

Genetic Skin Disorders

Genetic Skin Disorders

This valuable text represents a comprehensive survey of well over 300 distinct inherited dermatologic conditions.

Author: Virginia Sybert

Publisher: Oxford University Press

ISBN: 9780199774401

Category: Medical

Page: 784

View: 890

This valuable text represents a comprehensive survey of well over 300 distinct inherited dermatologic conditions. Each disease entry follows a consistent format, allowing the clinician to quickly scan and access key information for differential diagnosis. Each entry contains sections devoted to dermatologic features, associated clinical abnormalities, histopathology, biochemical and molecular information, treatment, mode of inheritance and recurrence risk, prenatal diagnosis, and information on differential diagnosis. In addition the author has included support group listings and detailed annotated references which will be of invaluable benefit for clinicians. The book is lavishly illustrated with color photos to illustrate the conditions and conditions are grouped into categories reflecting the primary site of the major dermatologic features to aid the clinician encountering a condition for the first time. The material is well- written and presented in a highly engaging, reader-friendly voice which makes the content interesting and accessible to the geneticist and non-geneticist alike. This invaluable resource reflects the author's extensive clinical experience and expertise in genetics and dermatology that provides a clear and critical synthesis of information on the genetics of diseases affecting the skin. Any clinician faced with a patient in whom the possibility for a genetic disorder of the skin exists will find this book a practical tool of immense interest. The new edition reflects a decade of new research advances in our understanding of the molecular basis for these conditions. Major additions have been added for over 150 of the entries, including information on treatment advances and advances in the natural history of disorders. All references have been updated as well as support group information and website resources.
Categories: Medical

Beh et s Disease

Beh  et s Disease

This book, besides reviewing basic and clinical aspects of Behçet's disease, covers the latest findings, including genetic studies and treatment with biologics for the disease.

Author: Yoshiaki Ishigatsubo

Publisher: Springer

ISBN: 9784431544876

Category: Medical

Page: 176

View: 659

This book, besides reviewing basic and clinical aspects of Behçet's disease, covers the latest findings, including genetic studies and treatment with biologics for the disease. Although the cause of Behçet's disease is still unknown, it is well known that genetic factors, such as HLA-B51, are involved in its development. Recently, novel susceptibility loci including IL10, IL23R-IL12RB2, and endoplasmic reticulum aminopeptidase 1 have been identified, providing new insights into the pathogenesis of the disease. In addition to basic research, the beneficial efficacy of anti-TNF-alpha monoclonal antibodies has also been suggested for not only uveitis associated with the disease but also other subtypes of the disease such as entero-, vasculo-, and neuro- Behçet's disease. Behçet's Disease: From Genetics to Therapies provides essential information both for basic researchers working in the fields of immunology, inflammation, and genetics, and for clinical physicians who are interested in Behçet's disease, such as ophthalmologists, rheumatologists, dermatologists, gastroenterologists, neurologists, and vascular surgeons.​
Categories: Medical

Rook s Textbook of Dermatology

Rook s Textbook of Dermatology

2 Moss C, Savin J. Dermatology and the New Genetics. Oxford: Blackwell Science, 1995. 3 Novice FM, Collison DW, Burgdorf WHC, Esterly NB.

Author: Tony Burns

Publisher: John Wiley & Sons

ISBN: 9781405141048

Category: Medical

Page: 4568

View: 121

The late Arthur Rook established the Textbook of Dermatology as the most comprehensive work of reference available to the dermatologist and it enjoys instant name recognition. Each subsequent edition has been expanded as the subject has developed and the book remains the ultimate source of clinical information for the trainee and practising dermatologist alike. Rook's Textbook of Dermatology covers all aspects of skin disease from basic science through pathology and epidemiology to clinical practice. Long recognized for its unparalleled coverage of diagnosis, this clinical classic earned its reputation as a definitive source of information. New features of this Seventh Edition include: Two new Editors, Neil Cox and Christopher Griffiths, join the team Every chapter is updated and several are completely rewritten from scratch Completely new chapter on AIDS and the Skin Traditional emphasis on diagnosis preserved More coverage of treatment in each of the disease-specific chapters
Categories: Medical

Genetic Disorders of the Skin

Genetic Disorders of the Skin

... Genetic Counseling Center Rhode Island Hospital Providence , Rhode Island Lee ... of Environmental Dermatology Presbyterian Hospital New York , New York ...

Author: Joseph C. Alper

Publisher: Year Book Medical Pub

ISBN: UOM:39015018891955

Category: Medical

Page: 378

View: 609

Categories: Medical

Genetic Skin Disorders

Genetic Skin Disorders

This comprehensive, heavily illustrated reference work on genetic skin diseases will be invaluable to dermatologists, geneticists, and pediatricians with a special interest in skin disorders.

Author: Virginia P. Sybert

Publisher: Oxford University Press, USA

ISBN: UOM:39015040045596

Category: Medical

Page: 675

View: 868

This comprehensive, heavily illustrated reference work on genetic skin diseases will be invaluable to dermatologists, geneticists, and pediatricians with a special interest in skin disorders. Its format is designed for easy clinical use; each condition is described in terms of major and minor dermatologic features, associated clinical abnormalities, histopathology, biochemistry and molecular biology, treatment, mode of inheritance and recurrence risks, prenatal and differential diadgnosis.
Categories: Medical