We have reviewed recent advances of clinical features of EPP, genetic
characteristics of EPP, and mice models of EPP. Further studies of genetic
analysis and FECH-deficient mice will provide us the new strategy for the
treatment of EPP.
Author: Naoki Oiso
Publisher: BoD – Books on Demand
ISBN: 9789535109716
Category: Medical
Page: 170
View: 625
This book presents current topics in genetics in the dermatologic field. Various skin disorders are inherited as mendelian inheritance. Genetic skin disorders are caused by mutations in the genes encoding proteins expressing in skin, skin appendages, melanocytes and immune-associated cells. Identification of genes and elucidation of function of the encoded proteins may provide novel strategies to overcome the disorders. We hope that this book offers sufficient current information in each disorder to scientists, physicians and dermatologists, and that novel therapies will be provided to affected individuals via these chapters.