Emerging Targets for Drug Addiction Treatment

Emerging Targets for Drug Addiction Treatment

Includes bibliographical references and index.

Author: Juan Canales

Publisher: Nova Science Pub Incorporated

ISBN: 1620819139

Category: Psychology

Page: 230

View: 202

In this book the editor presents a collection of state-of-the-art, authoritative overviews in the field of treatment for drug and behavioral addictions. Both clinical and basic research perspectives are integrated in the book, covering recent findings in the field of stimulant, cannabis and opioid abuse, as well as non-drug addictions, with an emphasis in novel pharmacological interventions and potential receptor targets recently identified. The intended audience of this exciting selection is broad, encompassing clinicians, researchers and graduate students who seek advanced knowledge and up-to-date information in this rapidly moving field of enquiry.
Categories: Psychology

Emerging Targets for Drug Addiction Treatment

Emerging Targets for Drug Addiction Treatment

In this book the editor presents a collection of state-of-the-art, authoritative overviews in the field of treatment for drug and behavioral addictions.

Author: Juan Canales

Publisher: Nova Science Publishers

ISBN: 1620819546

Category: Drug addiction

Page: 240

View: 459

In this book the editor presents a collection of state-of-the-art, authoritative overviews in the field of treatment for drug and behavioral addictions. Both clinical and basic research perspectives are integrated in the book, covering recent findings in the field of stimulant, cannabis and opioid abuse, as well as non-drug addictions, with an emphasis in novel pharmacological interventions and potential receptor targets recently identified. The intended audience of this exciting selection is broad, encompassing clinicians, researchers and graduate students who seek advanced knowledge and up-to-date information in this rapidly moving field of enquiry.
Categories: Drug addiction

New Paradigms in Neuroscience and Related Targets for Drug Discovery

New Paradigms in Neuroscience and Related Targets for Drug Discovery

Drug discovery for the treatment of substance use disorders: novel targets, repurposing, and the need for new paradigms. Curr. Opin. Pharmacol. 35, 120–124. doi:10.1016/j.coph.2017.08.009 Chung, T., and Clark, D. B. (2014).

Author: Salvatore Salomone

Publisher: Frontiers Media SA

ISBN: 9782889638208

Category:

Page:

View: 974

Categories:

Emerging Targets and Therapeutics in the Treatment of Psychostimulant Abuse

Emerging Targets and Therapeutics in the Treatment of Psychostimulant Abuse

Nevertheless, these findings highlight the emergence of the a3b4* nAChR as a new potential target for the ... this was considered to be a new and somewhat controversial approach to therapeutic intervention in tobacco addiction.

Author: Linda P. Dwoskin

Publisher: Academic Press

ISBN: 9780124201774

Category: Medical

Page: 656

View: 176

This new volume of Advances in Pharmacology presents the emerging targets and therapeutics in the treatment of psychostimulant abuse. With a variety of chapters and the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike. Contributions from the best authors in the field An essential resource for pharmacologists, immunologists, and biochemists
Categories: Medical

New Treatments for Addiction

New Treatments for Addiction

New and improved therapies to treat and protect against drug dependence and abuse are urgently needed. In the United States alone about 50 million people regularly smoke tobacco and another 5 million are addicted to other drugs.

Author: National Research Council

Publisher: National Academies Press

ISBN: 0309166659

Category: Medical

Page: 320

View: 133

New and improved therapies to treat and protect against drug dependence and abuse are urgently needed. In the United States alone about 50 million people regularly smoke tobacco and another 5 million are addicted to other drugs. In a given year, millions of these individuals attemptâ€"with or without medical assistanceâ€"to quit using drugs, though relapse remains the norm. Furthermore, each year several million teenagers start smoking and nearly as many take illicit drugs for the first time. Research is advancing on promising new means of treating drug addiction using immunotherapies and sustained-release (depot) medications. The aim of this research is to develop medications that can block or significantly attenuate the psychoactive effects of such drugs as cocaine, nicotine, heroin, phencyclidine, and methamphetamine for weeks or months at a time. This represents a fundamentally new therapeutic approach that shows promise for treating drug addiction problems that were difficult to treat in the past. Despite their potential benefits, however, several characteristics of these new methods pose distinct behavioral, ethical, legal, and social challenges that require careful scrutiny. Such issues can be considered unique aspects of safety and efficacy that are fundamentally related to the distinct nature and properties of these new types of medications.
Categories: Medical

Neuroscience for Addiction Medicine From Prevention to Rehabilitation Methods and Interventions

Neuroscience for Addiction Medicine  From Prevention to Rehabilitation   Methods and Interventions

The modulation of appetitive behavior via direct or indirect manipulation of the mesolimbic DA system is the largest explored approach for the development of drug abuse treatments. The drug targets described above offer new ...

Author:

Publisher: Elsevier

ISBN: 9780444637406

Category: Psychology

Page: 488

View: 334

Neuroscience for Addiction Medicine: From Prevention to Rehabilitation - Methods and Interventions is the latest volume from Progress in Brain Research focusing on new trends and developments in addiction research. This established international series examines major areas of basic and clinical research within neuroscience, as well as popular emerging subfields such as addiction. This volume takes an integrated approach to review and summarize some of the most recent progress from the subfield of addiction research, with particular emphasis on potential applications in a clinical setting. Explores new trends and developments in basic and clinical research in the addiction subfield of neuroscience Uses an integrated approach to review and summarize recent progress Emphasizes potential applications in a clinical setting Enhances the literature of neuroscience by further expanding the established international series Progress in Brain Research
Categories: Psychology

Handbook of Cannabis and Related Pathologies

Handbook of Cannabis and Related Pathologies

Application of technology in the prevention and treatment of substance use disorders and related problems: opportunities and challenges. Substance Use and Misuse, ... In J. Canales (Ed.), Emerging targets for drug addiction treatment.

Author: Victor R. Preedy

Publisher: Academic Press

ISBN: 9780128008270

Category: Medical

Page: 1170

View: 465

Handbook of Cannabis and Related Pathologies: Biology, Pharmacology, Diagnosis, and Treatment is the first book to take an interdisciplinary approach to the understanding of cannabis use and misuse. Recent worldwide trends toward decriminalizing marijuana for medical use have increased legal use of the drug and recreational use remains high, making cannabis one of the most commonly used drugs. Cannabis has a wide range of adverse neurological effects, and use and abuse can lead to physical, social, and psychopathological issues that are multifarious and complex. Effective understanding and treatment requires knowledge of the drug’s effects from across scientific disciplines. This book provides an overview of the biological and pharmacological components of the cannabis plant, outlines its neurological, social, and psychopathological effects, assists in the diagnosis and screening for use and dependency, and aids researchers in developing effective treatments for cannabis-related issues and disorders. Fully illustrated, with contributions from internationally recognized experts, it is the go-to resource for neuroscientists, pharmacologists, pathologists, public-health workers, and any other researcher who needs an in-depth and cross-disciplinary understanding of cannabis and its effects. Comprehensive chapters include an abstract, key facts, mini dictionary of terms, and summary points Presents illustrations with at least six figures, tables, and diagrams per chapter Provides a one-stop-shopping synopsis of everything to do with cannabis and its related pathology, from chemicals and cells, individuals and communities, and diagnosis and treatment Offers an integrated and informed synopsis of the complex issues surrounding cannabis as a substance, its use, and its misuse
Categories: Medical

The Brain as a Drug Target

The Brain as a Drug Target

Brain Nicotinic Receptors as Emerging Targets for Drug Addiction: Neurobiology to Translational Research Shafiqur Rahman ... As a result, there is an increasing interest in developing nAChR-based therapies for the treatment of addictive ...

Author: Shafiqur Rahman

Publisher: Academic Press

ISBN: 9780123855060

Category: Medical

Page: 453

View: 690

The brain is protected by the blood-brain barrier and this barrier prevents many drugs from entering the brain. This volume discusses various drug delivery and targeting strategies that are being developed to enhance the transport and distribution of drugs into the brain. * Discusses new discoveries, approaches, and ideas * Contributions from leading scholars and industry experts * Reference guide for researchers involved in molecular biology and related fields
Categories: Medical

Trace Amines and Neurological Disorders

Trace Amines and Neurological Disorders

Trace amine-associated receptor 1: a promising target for the treatment of psychostimulant addiction. ... Volkow ND, Morales M. The brain on drugs: from reward to addiction. ... Emerging targets for drug addiction treatment.

Author: Tahira Farooqui

Publisher: Academic Press

ISBN: 9780128036167

Category: Medical

Page: 432

View: 629

Trace Amines and Neurological Disorders: Potential Mechanisms and Risk Factors explores trace amines which, under normal conditions, are present in the mammalian brain and peripheral nervous tissues at very low (nanomolar) concentrations. However, in a diverse array of human pathologies ranging from substance abuse, depression, attention deficit hyperactivity disorder, eating disorders, schizophrenia, and other neurological and neuropsychiatric diseases, the levels of trace amines are unusually high with an imbalance in their functions. Furthermore, the rapid turnover of trace amines is evidenced by their dramatic increases following treatment with monoamine oxidase inhibitors (MAOI) or deletion of the MAO genes. This suggests that the concentration of trace amines may be considerably higher at neuronal synapses than predicted by steady-state measures, implicating some pathophysiological role. Therefore, understanding molecular mechanisms and developing selective agonists and antagonists for trace amine-associated receptors (TAARs) has become a good approach for treating these diseases. Although the effects of trace amines at low physiological concentrations in mammalian species have been difficult to demonstrate, they may serve to maintain the neuronal activity of other monoamine neurotransmitters by possessing postsynaptic modulatory effects, particularly dopamine and serotonin, within defined physiological limits. Such an effect of trace amines makes them ideal candidates for the development of novel therapeutics for a wide range of human disorders. This book presents up-to-date, cutting-edge, and comprehensive information on the link between trace amines and neurological disorders. Focuses on recent findings on trace amines, providing insights into the functional significance, molecular mechanisms, and biological relevance of TAARS in neurological disorders Edited work with chapters authored by leaders in the field from around the globe, the broadest, most expert coverage available Provides cutting-edge research on trace amines-mediated signaling in vertebrate model systems
Categories: Medical

Concepts of Chemical Dependency

Concepts of Chemical Dependency

... Textbook of Substance Abuse Treatment. Washington, DC: American Psychiatric Association, Inc. Ross, S. (2012). Serotonergic hallucinogens and emerging targets for addiction pharmacotherapies. Psychiatric Clinics ofNorth America, ...

Author: Harold E. Doweiko

Publisher: Cengage Learning

ISBN: 9781305177406

Category: Psychology

Page: 640

View: 335

CONCEPTS OF CHEMICAL DEPENDENCY, Ninth Edition, provides comprehensive coverage and the latest information on a full spectrum of substance use disorders and the compounds commonly abused. Topics include the abuse of and addiction to alcohol; how the active agent in marijuana, THC, affects neural growth and development; the emerging body of evidence suggesting a relationship between marijuana abuse and psychotic disorders; the emerging body of evidence suggesting that marijuana is not as benign as it was thought to be a few years ago; and the abuse of cough syrups. Adding to the book's usefulness and relevance, Doweiko also covers topics not usually discussed in other substance abuse texts, including abuse of anabolic steroids, inhalants, infectious diseases associated with substance abuse, how the “war on drugs” has actually contributed to the problem of substance abuse/addiction in this country, and the “medical marijuana” debate. This edition includes new information on synthetic marijuana, mephredone, and dextromethorphan, among other substances; updates reflecting the new DSM-5; and a new chapter on the Biopsychosocial Model of Addiction. Students report that they appreciate the author's balanced approach, which allows them to form their own opinions, in contrast to some books that “preach” that “drugs are bad for you.” Important Notice: Media content referenced within the product description or the product text may not be available in the ebook version.
Categories: Psychology