Genomic Essentials for Graduate Level Nurses

Genomic Essentials for Graduate Level Nurses

Pharmacogenetics/pharmacogenomics, a rapidly growing field, has become one of the most important aspects for personalized/precision medicine. This subject field is expected to revolutionize clinical practice in the near future even ...

Author: Diane C. Seibert

Publisher: DEStech Publications, Inc

ISBN: 9781605950945

Category: Medical

Page: 454

View: 661

Presents genetics and genomic essentials specifically for graduate-level nursesPrenatal care, cardiology, cancer and other disease systems covered in depth by chapter expertsKey chapter devoted to ethical and legal issues and to future technology Designed as both a nursing reference and course text, this book presents genetics and genomic essentials specifically for graduate-level nurses. Preliminary chapters cover the basics of genetics, risk assessment and genetic testing. With chapter contributions by topic experts, the remainder of the book is organized by disease system and covers genetics and genomics in prenatal care, neurology, cancer, respiratory function, cardiology, pharmacogenomics, hematology and others. Key chapters on ethical and legal issues and future technology are also included. This volume is well-suited for nursing faculty, nursing students, nurse leaders, and other nursing professionals with a need for further information on genetics and genomics in a nursing role and across a variety of specialties.
Categories: Medical

Concepts in Pharmacogenomics

Concepts in Pharmacogenomics

To meet this need, ASHP's Concepts in Pharmacogenomics has been completely updated for the second edition, covering both the fundamentals of pharmacogenomics and the latest genomic technologies.

Author: Martin M. Zdanowicz

Publisher:

ISBN: 1585285161

Category:

Page:

View: 599

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Essentials of Pharmacogenomics

Essentials of Pharmacogenomics

This book is written to serve as a principal textbook for introductory pharmacogenomics course, emphasizing pedagogy along with applications in a way useful for students along with professionals needing an accessible resource.

Author: P. B. Mahajan

Publisher: Wiley

ISBN: 1118342674

Category: Medical

Page: 608

View: 909

This book is written to serve as a principal textbook for introductory pharmacogenomics course, emphasizing pedagogy along with applications in a way useful for students along with professionals needing an accessible resource. The text covers each of the important areas of pharmacogenomics – fundamental principles, relevant technologies, clinical applications, and societal issues. It uses diagrams, flow charts, tables and boxed material in each chapter. The author – who himself teaches and designed a pharmacogenomics – includes practice questions, problems and answers, and a bibliography including web links at the end of each chapter.
Categories: Medical

Essentials of Genomic and Personalized Medicine

Essentials of Genomic and Personalized Medicine

Many pharmacogenomic approaches (e.g., targeting therapy to a specific-identified population), would limit the indicated population. Complexity of use (e.g., dose adjustments, need for pre-testing) is also commercially undesirable and ...

Author: Geoffrey S. Ginsburg

Publisher: Academic Press

ISBN: 0080958117

Category: Science

Page: 850

View: 609

Derived from the comprehensive two-volume set, Genomic and Personalized Medicine also edited by Drs. Willard and Ginsburg, this work serves the needs of the evolving population of scientists, researchers, practitioners and students that are embracing one of the most promising avenues for advances in diagnosis, prevention and treatment of human disease. From principles, methodology and translational approaches to genome discoveries and clinical applications, Essentials of Genomic and Personalized Medicine will be a valuable resource for various professionals and students across medical disciplines, including human genetics and genomics, oncology, neuroscience, gene therapy, molecular medicine, pharmacology, and biomedical sciences. Updates with regard to diagnostic testing, pharmacogenetics, predicting disease susceptibility, and other important research components as well as chapters dedicated to cardiovascular disease, oncology, inflammatory disease, metabolic disease, neuropsychiatric disease, and infectious disease, present this book as an essential tool for a variety of professionals and students who are endeavouring into the developing the diverse and practical field of genomic and personalized medicine. * Full color throughout * Includes contributions on genetic counselling, ethical, legal/regulatory, and social issues related to the practice of genomic medicine from leaders in the field * Introductory chapter highlights differences between personalized and traditional medicine, promising areas of current research, and challenges to incorporate the latest research discoveries and practice * Ancillary material includes case studies and lab questions which highlight the collaborative approach to the science
Categories: Science

Principles of Pharmacogenetics and Pharmacogenomics

Principles of Pharmacogenetics and Pharmacogenomics

"This book is intended to introduce the field of phamacogenetics and pharmacogenomics to health care professionals. It brings together the latest informaiton about how human genetics impacts drug response phenotypes.

Author: Russ B. Altman

Publisher: Cambridge University Press

ISBN: 9780521885379

Category: Medical

Page: 269

View: 547

"This book is intended to introduce the field of phamacogenetics and pharmacogenomics to health care professionals. It brings together the latest informaiton about how human genetics impacts drug response phenotypes. It is written to enable the reader to undestand the current knowledge and challenges to the field"--Provided by publisher.
Categories: Medical

Essentials of Cancer Genomic Computational Approaches and Precision Medicine

 Essentials of Cancer Genomic  Computational Approaches and Precision Medicine

The investigation of the connection between hereditary qualities and medication work is most normally known as pharmacogenetics or pharmacogenomics. Pharmacogenomics is a valid, recognized, and personalized approach of treatment and has ...

Author: Nosheen Masood

Publisher: Springer Nature

ISBN: 9789811510670

Category: Medical

Page: 499

View: 259

This book concisely describes the role of omics in precision medicine for cancer therapies. It outlines our current understanding of cancer genomics, shares insights into the process of oncogenesis, and discusses emerging technologies and clinical applications of cancer genomics in prognosis and precision-medicine treatment strategies. It then elaborates on recent advances concerning transcriptomics and translational genomics in cancer diagnosis, clinical applications, and personalized medicine in oncology. Importantly, it also explains the importance of high-performance analytics, predictive modeling, and system biology in cancer research. Lastly, the book discusses current and potential future applications of pharmacogenomics in clinical cancer therapy and cancer drug development.
Categories: Medical

Mastering Pharmacogenomics A Nurse s Handbook for Success

Mastering Pharmacogenomics  A Nurse s Handbook for Success

After the learner identifies the gaps in his or her knowledge and skills, it becomes essential to identify learning activities and desired outcomes needed to address these areas. Lectures and contemporary readings combining active ...

Author: Dale Halsey Lea

Publisher: Sigma Theta Tau

ISBN: 9781938835704

Category: Medical

Page: 264

View: 883

Pharmacogenomics, the study of the role of genetics in drug response, has developed into a critical new area in battling disease and improving outcomes. As our knowledge of the human genome grows, and with the advent of next-generation sequencing technologies, the role of genetic research is evolving to guide therapy and prevent many diseases and mitigate side-effects of current treatments. As a pivotal member of the healthcare team, nurses must acquire competency in pharmacogenomics to deliver optimal patient care in the 21st century. Mastering Pharmacogenomics provides nursing professionals with a foundational knowledge of human genetics and genomics that can be applied in optimizing drug therapy and patient care delivery. Coverage includes: Essential pharmacogenomics competencies for registered nurses Genomics technologies and resources Critical properties of drug response and disposition Covered specialties include obstetrics and prenatal patients, pediatrics, older adult patients, and oncology Ethics and patient careFuture developments in technology and delivery
Categories: Medical

Essentials of Autopsy Practice

Essentials of Autopsy Practice

This chapter describes the basic concepts of pharmacogenomics, and how genetics and toxicology can aid forensic pathology, and together form an essential part of the COD and manner of death (MoD) investigation.

Author: Guy N. Rutty

Publisher: Springer Science & Business Media

ISBN: 9781447152705

Category: Medical

Page: 153

View: 511

This book covers new and exciting topics which have emerged in the area of autopsy recently, including the three different post-mortem CT-angiography systems currently available to practitioners in this field; a highly topical chapter on the role of genetic abnormalities in the handling of drugs within the body and how this can affect the interpretation of toxicological results in relation to how the drug may have caused or contributed to death; an update on the current classification and considerations related to deaths due to hanging; a review of injuries and fatalities caused by animals including post-mortem scavenging; an authoritative review of poisons and toxins from water and the life that inhabits it; and recent advances in knowledge in the use of entomology as an investigative tool as well as knowledge related to colonisation of cadavers by insects, animals and birds. Essentials of Autopsy Practice: Advances, Updates and Emerging Technologies is a multi-subject book, aimed at different grades of practitioners, from different practice areas, covering topics that are currently discussed and anticipated to be discussed in the field of autopsy practice over the next few years.​
Categories: Medical

Pharmacogenomics An Introduction and Clinical Perspective

Pharmacogenomics An Introduction and Clinical Perspective

A COMPLETE INTRODUCTORY TEXT TO THE FIELD OF PHARMACOGENOMICS The only pharmacogenomics resource to feature a global author team comprised of PharmDs, MDs, PhDs and social scientists, Pharmacogenomics offers an essential, highly accessible ...

Author: Joseph S. Bertino

Publisher: McGraw Hill Professional

ISBN: 9780071813716

Category: Medical

Page: 288

View: 876

A COMPLETE INTRODUCTORY TEXT TO THE FIELD OF PHARMACOGENOMICS The only pharmacogenomics resource to feature a global author team comprised of PharmDs, MDs, PhDs and social scientists, Pharmacogenomics offers an essential, highly accessible survey of this dynamic discipline. You will find thorough coverage of all need-to-know topics, from individual molecules to systemic diseases, plus an examination of the latest technologies that are constantly reshaping the field. Pharmacogenomics is cohesively organized into two sections, the first of which reviews basic aspects of pharmacogenomics, including ethics, regulatory, science, and drug metabolism, along with a "mini" course in molecular genetics and testing. The second section highlights the practical application of pharmacogenomics in cardiovascular medicine, immunology, neurology, and other specialties. FEATURES Important overview of general pharmacogenomics and pharmacogenetics concepts, including genetic variation in signal transduction and targets, plus a review of the genetic concepts of pharmacogenomics Discussion of regulatory considerations in pharmacogenomics Focus on the role of health care professionals along with a review of related privacy issues, as well as broader ethical, legal, and social considerations In-depth chapters on drug metabolism and transporters Practical, step-by-step guidance on public access to pharmacogenomic testing and patient counseling Up-to-date coverage of non-genetic influences on pharmacogenomics Emphasis on gene-drug interactions Numerous tables and figures Chapter-ending references Concise learning objectives at the beginning of each chapter Case studies to familiarize you with the clinical relevance of pharmacogenomics in each specialty
Categories: Medical

OMICS

OMICS

Polymorphisms of alpha adducin and salt-sensitivity in patients with essential hypertension. Lancet 349: 1353–1357. Daly, A. K. (2003). Pharmacogenetics of the major polymorphic metabolizing enzymes. Fund. Clin. Pharmacol. 17: 27–41.

Author: Debmalya Barh

Publisher: CRC Press

ISBN: 9781439850091

Category: Medical

Page: 622

View: 351

A reflection of the explosion of research and development in this field, OMICS: Biomedical Perspectives and Applications explores applications of omics in bioinformatics, cancer research and therapy, diabetes research, plant science, molecular biology, and neurosciences. A select editorial panel of experts discusses their cutting edge omics research and novel technologies, supplying a basic platform of methods and applications and a resource for enhanced cross-pollination in a multiomics approach to future endeavors in the fertile fields of omics research. After an introduction on the omics universe, the book presents modern omics and its applications in nanotechnology, genomics, proteomics, metagenomics, toxicogenomics, immunomics, nutrigenomics, diabetes, neurology, cardiology, and cancer to name just a few. The book begins with an overview of omics and omic technologies such as cellomics, glycomics, and lipidomics. It also discusses bioinformatics, demonstrating how it can be a tool in omics, and examines the various approaches of omics technology in toxicology research and applications in biomedical sciences. While there are a long list of omics books available, most focus narrowly on one area. Presenting a wide view of the current status of integrative omics, this resource contains complete coverage of omics in research and therapy, ranging from neuroscience to cardiology. It collates recent developments in the field into a state-of-the-art framework for this discipline.
Categories: Medical