The liver is of central importance to the entire organism due to its diverse functions in metabolism, its ability to detoxify and excrete, the hepatic formation and inactivation of mediators, and its involvement in non-specific defence ...
Author: R. Schmid
The liver is of central importance to the entire organism due to its diverse functions in metabolism, its ability to detoxify and excrete, the hepatic formation and inactivation of mediators, and its involvement in non-specific defence mechanisms. Thus, extrahepatic manifestations of liver disease are often decisive for the disease course. In the last few years, knowledge about interaction between the liver and other organs or systems - e.g. kidneys, GI tract, skeleton, endocrine, haematopoietic and nervous sytems - has increased considerably. Thus many extrahepatic manifestations of liver disease can now be better understood and are more accessible to diagnosis and therapy. The IXth International Congress on Liver Diseases brought together experts from around the world to give information on new developments in this field which are important both for research and clinical work. These proceedings will therefore be required reading for all researchers and clinicians dealing with effectsof liver diseases on the entire organism.
Dr. Younossi is a highly-esteemed expert in Hepatitis C Virus (HCV), and for the first time in Clinics in Liver Disease, he has compiled articles that specifically address the extrahepatic manifestation of HCV.
Author: Zobair M. Younossi
Publisher: Elsevier Health Sciences
Dr. Younossi is a highly-esteemed expert in Hepatitis C Virus (HCV), and for the first time in Clinics in Liver Disease, he has compiled articles that specifically address the extrahepatic manifestation of HCV. Articles are specifically devoted to the following topics: Hepatitis C: A Systemic Disease; Rheumatologic Manifestations of HCV; Cardiovascular Manifestations on HCV; Metabolic Manifestations of HCV (DM, Dyslipidemia); Renal Manifestations of HCV; Lymphoproliferative Disorders Associated with HCV; Depression and HCV; Neurologic Manifestations of HCV; Non-HCC Malignancies in HCV; Dermatologic Manifestations of HCV; Fatigue and Patient-reported Outcomes in HCV; Economic Burden of HCV; and Endocrine Manifestations of HCV (non-dabetes). The thorough coverage of systemic issues will give clinicians the information they need to effectively manage the HCV patient with other health issues.
This book presents up-to-date, practically oriented information on major topics in chronic hepatitis C. The coverage encompasses epidemiology; diagnosis, including molecular methods; treatment and challenges; and the management of co ...
Author: Resat Ozaras
This book presents up-to-date, practically oriented information on major topics in chronic hepatitis C. The coverage encompasses epidemiology; diagnosis, including molecular methods; treatment and challenges; and the management of co-infections. Readers will find guidance on pretherapeutic evaluation with respect to disease severity and extrahepatic manifestations. Resistance to antiviral treatment and its management are discussed, and the nature of optimal follow-up is addressed in detail. Treatment of HCV/HIV co-infection is considered separately, and the approach in special patient populations is thoroughly examined. Chronic Hepatitis C will be of high value for general practitioners and specialists in gastroenterology, infectious diseases, and internal medicine. It will be international in scope in terms of both authorship and appeal.
This book helps scientists, clinicians and other interested individuals understand recent clinical advances and challenges for the future.
Author: Tatsuo Miyamura
This book helps scientists, clinicians and other interested individuals understand recent clinical advances and challenges for the future. It covers many basic aspects of the pathogenesis of chronic hepatitis C, HCV infections in particular populations, approaches to therapy, and prevention and control of HCV Infection. The book provides a succinct review of the large amount of data generated by multiple groups over the past two decades that has revealed the natural history of HCV infection. Similarly, it summarizes current understanding of the origins of HCV-associated hepatocellular carcinoma, cirrhosis and hepatic fibrosis. Extra-hepatic manifestation and metabolic disorders related to HCV infection are described. In this volume, these clinically important aspects of HCV infection are comprehensively described. Highlights are description of newly developed direct- acting antivirals. The authors represent a worldwide distribution of leaders in the field reflecting the global nature of HCV infection. Based on recent data concerning the genetic- and geographical diversity of HCV, and increased global disease burden of HCV infection, challenges for global control of HCV infections are described.
This second edition expands the coverage of treatment of various difficult-to-treat patients and will be a welcome guide to the physician in both clinical decision-making and in explaining the benefits and side-effects to the patient.
Author: Thierry Poynard
Publisher: CRC Press
Chronic hepatitis B and C affect 520 million people worldwide, and are a major cause of chronic liver disease and of mortality, despite the efficacy of the vaccine. Hepatitis B and C: Management and Treatment second edition provides a practical explanation of the natural history and management of the disease, and examines the benefits of the most recent drugs, and their effects, whether used in isolation or as part of a combination therapy. This second edition expands the coverage of treatment of various difficult-to-treat patients and will be a welcome guide to the physician in both clinical decision-making and in explaining the benefits and side-effects to the patient.
A Practical Guide to Understanding, Treating & Living with Hepatitis & Liver Melissa Palmer ... Most of these extrahepatic manifestations are due to immunemediated diseases . However , HCV has also been found in various other parts of ...
Author: Melissa Palmer
Category: Health & Fitness
In the United States alone, more than four million people are infected with the hepatitis C virus, and chronic liver disease is the twelfth leading cause of death. In this revised and updated edition of her groundbreaking 2000 book, renowned hepatologist Dr. Melissa Palmer discusses all facets of liver disease, from symptoms and tests to treatment options and lifestyle changes. In addition, this comprehensive handbook reveals cutting-edge research on the dangers of hepatitis C, one of the world's fasting-growing microbial threats.
Author: Lawrence S. FriedmanPublish On: 2017-08-01
3 - Hepatitis A and Hepatitis E -- Hepatitis A Virus -- MOLECULAR BIOLOGY -- EPIDEMIOLOGY AND RISK FACTORS -- PATHOPHYSIOLOGY -- Cholestatic Hepatitis -- Relapsing Hepatitis -- EXTRAHEPATIC MANIFESTATIONS -- Cholestatic Disease -- Relapsing ...
Author: Lawrence S. Friedman
Well-organized and vibrantly illustrated throughout, Handbook of Liver Disease is a comprehensive yet concise handbook providing authoritative guidance on key clinical issues in liver disease. The quick-reference outline format ensures that you'll find answers when you need them, and cover-to-cover updates keep you abreast of the recent rapid changes in the field. Written by leading international experts in hepatology, this reference is ideal for gastroenterologists, hepatologists, internists, family practitioners, trainees, and others who diagnose and manage patients with liver disorders. Uses a highly templated outline format, key points in each chapter, alert symbols, and highlighted review points to provide a "just the facts" approach to daily clinical questions on liver disease. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, Q&As, and references from the book on a variety of devices. Features expanded hepatitis chapters, including completely updated coverage of new, safe, and effective oral regimens for the treatment of hepatitis C. Provides completely updated coverage of: alcoholic liver disease * autoimmune hepatitis * portal hypertension * primary biliary cholangitis * hepatic tumors * cirrhosis * nonalcoholic liver disease * liver transplantation * and more. Includes the latest information on adolescents with liver disease moving into adult care. Covers the revised criteria for prioritizing liver transplantation using the MELDNa score, new options for the treatment of hepatocellular carcinoma, and improved management of hepatorenal syndrome.
Therefore, this book has been created by distinguished faculties from around the world to address the progress in our understanding of HCV infection and to review new treatment options, limitations, and accessibility of new therapeutic ...
Author: Martina Smolic
Publisher: BoD – Books on Demand
In the past few years, remarkable progress has been made in our understanding of HCV biology, pathogenesis of infection, and structure-function relationships. This has led to quantum advances in clinical efficacy and tolerability. Yet, in spite of this amazing progress, there remain obstacles to widespread successful treatment. These issues include biological failures even with direct-acting agents, lack of options for individual with organ failures, drug-drug interactions, access to medications either due to lack of availability or affordability, and psychiatric and social issues. These problems are likely to remain in the future. Therefore, this book has been created by distinguished faculties from around the world to address the progress in our understanding of HCV infection and to review new treatment options, limitations, and accessibility of new therapeutic options.
Hepatology 1998;28:1416–23. 109. Cacoub P, Buggisch P, Carrion JA, Cooke GS, Zignego AL, Beckerman R, Younossi Z. Direct medical costs associated with the extrahepatic manifestations of hepatitis C infection in Europe.
Author: Frederick J. Suchy
Publisher: Cambridge University Press
Liver disease in children is increasing in prevalence, placing a huge burden on healthcare systems and often requiring long-term management. Offering an integrative approach to the science and clinical practice of pediatric hepatology, this is the definitive reference text for improved diagnosis and treatment strategies. In the new edition of this authoritative text, chapters have been thoroughly revised in line with major advances in the field, such as recognizing the increased frequency of fatty liver disease, and how genetic testing has the potential to establish earlier diagnoses for a variety of diseases. Disorders covered include cholestasis, metabolic disorders and hepatitis, with their presentation across the spectrum of infancy, childhood and adolescence discussed. The indications and surgical aspects of liver transplant are explained and post-transplant care is described in detail. This is a valuable resource for pediatricians, hepatologists, gastroenterologists and all clinicians involved in the care of children with liver diseases.