Haemoglobinopathy Diagnosis

Haemoglobinopathy Diagnosis

This important text: Contains a practical, highly illustrated, approach to the laboratory diagnosis of haemoglobin disorders Includes "test-yourself" questions and provides an indispensable tool for learning and teaching Presents new ...

Author: Barbara J. Bain

Publisher: John Wiley & Sons

ISBN: 9781119579953

Category: Medical

Page: 448

View: 828

An updated, essential guide for the laboratory diagnosis of haemoglobin disorders This revised and updated third edition of Haemoglobinopathy Diagnosis offers a comprehensive review of the practical information needed for an understanding of the laboratory diagnosis of haemoglobin disorders. Written in a concise and approachable format, the book includes an overview of clinical and laboratory features of these disorders. The author focuses on the selection, performance, and interpretation of the tests that are offered by the majority of diagnostic laboratories. The book also explains when more specialist tests are required and explores what specialist referral centres will accomplish. The information on diagnosis is set in a clinical context. The third edition is written by a leading haematologist with a reputation for educational excellence. Designed as a practical resource, the book is filled with illustrative examples and helpful questions that can aide in the retention of the material presented. Additionally, the author includes information on the most recent advances in the field. This important text: • Contains a practical, highly illustrated, approach to the laboratory diagnosis of haemoglobin disorders • Includes “test-yourself” questions and provides an indispensable tool for learning and teaching • Presents new material on antenatal screening/prenatal diagnostic services • Offers myriad self-assessment case studies that are ideal for the trainee Written for trainees and residents in haematology, practicing haematologists, and laboratory scientists, Haemoglobinopathy Diagnosis is an essential reference and learning tool that provides a clear basis for understanding the diagnosis of haemoglobin disorders.
Categories: Medical

Haemoglobinopathy Diagnosis

Haemoglobinopathy Diagnosis

diagnostic. service. General. principles. The organisation of a haemoglobinopathy service depends on the ethnic mix of the population served and also on ...

Author: Barbara J. Bain

Publisher: John Wiley & Sons

ISBN: 9781119579991

Category: Medical

Page: 448

View: 787

An updated, essential guide for the laboratory diagnosis of haemoglobin disorders This revised and updated third edition of Haemoglobinopathy Diagnosis offers a comprehensive review of the practical information needed for an understanding of the laboratory diagnosis of haemoglobin disorders. Written in a concise and approachable format, the book includes an overview of clinical and laboratory features of these disorders. The author focuses on the selection, performance, and interpretation of the tests that are offered by the majority of diagnostic laboratories. The book also explains when more specialist tests are required and explores what specialist referral centres will accomplish. The information on diagnosis is set in a clinical context. The third edition is written by a leading haematologist with a reputation for educational excellence. Designed as a practical resource, the book is filled with illustrative examples and helpful questions that can aide in the retention of the material presented. Additionally, the author includes information on the most recent advances in the field. This important text: • Contains a practical, highly illustrated, approach to the laboratory diagnosis of haemoglobin disorders • Includes “test-yourself” questions and provides an indispensable tool for learning and teaching • Presents new material on antenatal screening/prenatal diagnostic services • Offers myriad self-assessment case studies that are ideal for the trainee Written for trainees and residents in haematology, practicing haematologists, and laboratory scientists, Haemoglobinopathy Diagnosis is an essential reference and learning tool that provides a clear basis for understanding the diagnosis of haemoglobin disorders.
Categories: Medical

Variant Haemoglobins

Variant Haemoglobins

This book covers 150 normal and variant haemoglobins that have been studied and carefully documented. Variant Haemoglobins has four introductory chapters followed by an invaluable atlas.

Author: Barbara J. Bain

Publisher: John Wiley & Sons

ISBN: 9781444347678

Category: Medical

Page: 260

View: 909

Variant Haemoglobins – A Guide to Identification is based on the premise that any single diagnostic technique offers only a very provisional identification of a variant haemoglobin. In routine diagnostic practice two techniques are needed as a minimum, with the results being interpreted in the light of the clinical details, blood count, blood film and ethnic origin. This book covers 150 normal and variant haemoglobins that have been studied and carefully documented. Variant Haemoglobins has four introductory chapters followed by an invaluable atlas. The introductory chapters cover the genetics of haemoglobin synthesis the principles of tests employed for identification common haemoglobins of major clinical or diagnostic importance thalassaemias and related conditions The atlas section comprises 170 full colour pages in which each variant haemoglobin or combination of haemoglobins is illustrated by cellulose acetate electrophoresis at alkaline pH, agarose gel electrophoresis at acid pH, isoelectric focusing and one or more HPLC traces. For ease of reference, the atlas pages are arranged according to the retention time of each haemoglobin on HPLC, this becoming increasingly the primary technique employed in haemoglobin identification. Bringing a mix of necessary scientific expertise and clinical knowledge, each author has more than 30 years experience in the diagnosis of variant haemoglobins. Providing otherwise unavailable information, this unique and practical guide is illustrated with over 700 high quality colour digital images plus flow charts and line diagrams covers common and important haemoglobin variants, in addition to many rarer ones is an essential reference source for diagnosis in the haematology laboratory A remarkably useful book, Variant Haemoglobins will be valuable for haematopathologists, clinical and laboratory haematologists in practice and in training and all laboratory staff involved in haemoglobinopathy diagnosis.
Categories: Medical

Haemophilia

Haemophilia

b HAEMOGLOBINOPATHY DIAGNOSIS By Barbara J. Bain Blackwell Science
Osney Mead , Oxford OX2 OEL UK ... in the diagnosis of haemoglobinopathies
are due to a failure in collecting correct laboratory data , or because of incorrect ...

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Publisher:

ISBN: NWU:35558005075664

Category:

Page:

View: 393

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Practical Management of Haemoglobinopathies

Practical Management of Haemoglobinopathies

Bain J. Haemoglobinopathy Diagnosis. Blackwell Science, 2001. 17. British Committee for Standards in Haematology. Oxford: Guidelines on the laboratory ...

Author: Iheanyi Okpala

Publisher: John Wiley & Sons

ISBN: 9781405140201

Category: Medical

Page: 256

View: 434

Presents a comprehensive picture of care, including diagnostic, therapeutic, and psychosocial aspects. The contributors cover basic science and epidemiological aspects of the public health challenge, but maintain a focus on the day to day issues encountered in dealing with affected people. Containing clear, practical advice, this text is an essential, practical resource to bridge the gap between expensive reference texts and smaller manuals. Practical Management of Haemoglobinopathies is an ideal for; Trainees and residents in haematology Hematologists in practice Healthcare professionals treating those with sickle cell disease and thalassaemia Why Buy This Book? Deals with practical problems encountered in the comprehensive care of affected individuals Each chapter written by an expert in the field Comprehensive coverage of basic science, laboratory diagnosis, psychosocial support and community care
Categories: Medical

New Scientist

New Scientist

The laboratories undertake phenotypic testing incorporating functional studies
and characterisation of the haemoglobin variants, prenatal diagnosis for major
haemoglobinopathies and DNA diagnostics of the haemoglobin disorders.

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Publisher:

ISBN: UOM:39015055745254

Category: Science

Page:

View: 144

Categories: Science

Pediatric Hematology

Pediatric Hematology

Pediatric Hematology is a collection of cutting-edge methods for investigating and detecting a wide variety of hematological disorders.

Author: Nicholas J. Goulden

Publisher: Springer Science & Business Media

ISBN: 9781592594337

Category: Medical

Page: 272

View: 478

Pediatric Hematology is a collection of cutting-edge methods for investigating and detecting a wide variety of hematological disorders. Here, the reader will find reliable molecular protocols for the diagnosis of Fanconi anemia and dyskeratosis congenita, immunodeficiency, and most forms of hemoglobinopathy. In addition, there are detailed methods for molecular human platelet antigen genotyping, an effective PCR procedure for thrombophilia screening, and protocols for fluorescent in situ hybridization. Since the measurement of minimal residual disease (MRD) provides a much more accurate risk-directed therapy, three methods are presented for detecting residual leukemia below the threshold of light microscopy, along with relatively simple, rapid, and cheap methods for the detection of MRD in ALL and AML.
Categories: Medical

Newborn Screening for Sickle Cell Disease and other Haemoglobinopathies

Newborn Screening for Sickle Cell Disease and other Haemoglobinopathies

This book gives an overview of diagnostic standards in newborn screening for sickle cell disease and examples of existing newborn screening programs.

Author: Stephan Lobitz

Publisher: MDPI

ISBN: 9783039216147

Category: Medical

Page: 162

View: 407

Newborn Screening for Sickle Cell Disease and other Haemoglobinopathies is a Special Issue of the International Journal of Neonatal Screening. Sickle cell disease is one of the most common inherited blood disorders, with a huge impact on health care systems due to high morbidity and high mortality associated with the undiagnosed disease. Newborn screening helps to make the diagnosis early and to prevent fatal complications and diagnostic odysseys. This book gives an overview of diagnostic standards in newborn screening for sickle cell disease and examples of existing newborn screening programs.
Categories: Medical

Hemoglobinopathies and Thalassemias

Hemoglobinopathies and Thalassemias

Author: Virgil F. Fairbanks

Publisher: Thieme Medical Publishers

ISBN: UOM:39015029959635

Category: Haemoglobinopathies

Page: 298

View: 833

Categories: Haemoglobinopathies

Journal of Medical Genetics

Journal of Medical Genetics

Most of those who thought screening was not justified had underestimated
haemoglobinopathy prevalence in the area . ... Effect of introducing antenatal
diagnosis on reproductive behaviour of families at risk for thalassaemia major . Br
Med J ...

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Publisher:

ISBN: OSU:32435018835124

Category: Genetics

Page:

View: 462

Categories: Genetics

Disorders of Hemoglobin

Disorders of Hemoglobin

This text is divided into eight distinct sections, and includes coverage of the molecular and genetic basis of hemoglobinopathies and thalassemias, their epidemiology and genetic selection, and the diagnosis and special treatments of ^D*b ...

Author: Martin H. Steinberg

Publisher: Cambridge University Press

ISBN: 0521632668

Category: Medical

Page: 1268

View: 375

Disorders of Hemoglobin stands tall as the definitive work on the genetics, pathophysiology, and clinical management of hemoglobinopathies and thalassemia. Drs. Steinberg, Forget, Higgs, and Nagel have gathered the world authorities on the science and clinical management of these disorders and created the authoritative textbook for researchers and clinicians alike.Authors describe the scientific basis of clinical features and provide clinicians with a clear background of disorders they treat and scientists with an essential link between their research and its clinical manifestation. Disorders of Hemoglobin is the only single-source reference on hemoglobinopathies for hematologists, pediatricians, clinical investigators, and geneticists worldwide.
Categories: Medical