Hepatitis B Virus and Liver Disease

Hepatitis B Virus and Liver Disease

This book provides a comprehensive, state-of-the art review of HBV infection and liver disease.

Author: Jia-Horng Kao

Publisher: Springer Nature

ISBN: 9789811636158

Category: Cancer

Page: 508

View: 366

This book provides a comprehensive, state-of-the art review of HBV infection and liver disease. It discusses new data on basic and translational medicine, including the viral life cycle, the immunopathogenesis of virus-induced chronic hepatitis, viral and host genetic factors affecting disease progression, and the mechanism of virus-induced hepatocarcinogenesis, as well as their potential applications in daily clinical practice. The clinical aspects of chronic HBV infection are examined in chapters on the global epidemiology, efficacy of HBV vaccination, natural history, novel biomarkers, co-infections with HCV, HDV or HIV, and management of special populations including children, pregnant women and patients undergoing immunosuppressive therapy. Further, it describes the advances and perspectives in the development of novel antiviral treatments for possible functional cure of HBV infection. In this second edition, authors provides recent updates in epidemiology, biomarkers, antivirus therapy, and novel therapy for functional cure of chronic hepatitis B virus infection. The book is a valuable resource for medical students, physicians, and researchers who are interested in management of patients with chronic HBV infection and investigation HBV infection.
Categories: Cancer

Hepatitis B The Virus the Disease and the Vaccine

Hepatitis B  The Virus  the Disease and the Vaccine

Toby K. Eisenstein Symposium Committee Chairperson Temple University School of Medicine Philadelphia, Pennsylvania 19140 This symposium is the thirteenth biennial clinical microbiology program sponsored by the Eastern Pennsylvania Branch of ...

Author: Irving Millman

Publisher: Springer Science & Business Media

ISBN: 0306417235

Category: Science

Page: 282

View: 228

Toby K. Eisenstein Symposium Committee Chairperson Temple University School of Medicine Philadelphia, Pennsylvania 19140 This symposium is the thirteenth biennial clinical microbiology program sponsored by the Eastern Pennsylvania Branch of the American Society for Microbiology in cooperation with the Philadelphia area medical schools and the Bureau of Laboratories of the Pennsylvania Department of Health. This year a generous contribution from Merck, Sharp and Dohme has helped to make the program a reality. The subject matter for this symposium represents an attractive spectrum of medical, biological and molecular approaches to the practical solution of a public health prob1em--name1y, prevention of infection with the hepatitis B virus. The symposium may be unique in that it focuses on a product which was first marketed less than three months ago, but included in the program are presen tations on two new approaches to hepatitis B vaccine production which may replace the one which is newly unveiled. The rapidity of progress in our present era of biological research is indeed astonishing.
Categories: Science

Viral Hepatitis

Viral Hepatitis

The 4th edition of Viral Hepatitis covers comprehensively the entire complex field of infections caused by all of the different hepatitis viruses, which affect many millions of people throughout the world with considerable morbidity and ...

Author: Howard C. Thomas

Publisher: John Wiley & Sons

ISBN: 9781118637333

Category: Medical

Page: 624

View: 417

The 4th edition of Viral Hepatitis coverscomprehensively the entire complex field of infections caused byall of the different hepatitis viruses, which affect many millionsof people throughout the world with considerable morbidity andmortality. Howard Thomas and Arie Zuckerman are joined by Anna Lok from theUSA and Stephen Locarnini from Australia as Editors. Theyhave recruited leading researchers and physicians from manycountries, who have produced an authoritative account of currentknowledge and research on this important infection, including newinsights into immune response to HBV and HCV. The result is a comprehensive account on all aspects of viralhepatitis, including rapid advances in the diagnosis, management,treatment and prevention of a complex infection, which in the caseof hepatitis B, C and D may lead to severe complications includingchronic hepatitis, cirrhosis and hepatocellular carcinoma. The latest edition of Viral Hepatitis offers an essentialresource of current information for hepatologists,gastroenterologists, infectious diseases specialists and otherclinicians, researchers, public health physicians and National andInternational Health Authorities.
Categories: Medical

Hepatitis and Liver Cancer

Hepatitis and Liver Cancer

The book presents ways to reduce the numbers of new HBV and HCV infections and the morbidity and mortality related to chronic viral hepatitis.

Author: Institute of Medicine

Publisher: National Academies Press

ISBN: 9780309146289

Category: Medical

Page: 252

View: 625

The global epidemic of hepatitis B and C is a serious public health problem. Hepatitis B and C are the major causes of chronic liver disease and liver cancer in the world. In the next 10 years, 150,000 people in the United States will die from liver disease or liver cancer associated with chronic hepatitis B virus (HBV) or hepatitis C virus (HCV) infections. Today, between 800,000 and 1.4 million people in the United States have chronic hepatitis B and between 2.7 and 3.9 million have chronic hepatitis C. People most at risk for hepatitis B and C often are the least likely to have access to medical services. Reducing the rates of illness and death associated with these diseases will require greater awareness and knowledge among health care workers, improved identification of at-risk people, and improved access to medical care. Hepatitis B is a vaccine-preventable disease. Although federal public health officials recommend that all newborns, children, and at-risk adults receive the vaccine, about 46,000 new acute cases of the HBV infection emerge each year, including 1,000 in infants who acquire the infection during birth from their HBV-positive mothers. Unfortunately, there is no vaccine for hepatitis C, which is transmitted by direct exposure to infectious blood. Hepatitis and Liver Cancer identifies missed opportunities related to the prevention and control of HBV and HCV infections. The book presents ways to reduce the numbers of new HBV and HCV infections and the morbidity and mortality related to chronic viral hepatitis. It identifies priorities for research, policy, and action geared toward federal, state, and local public health officials, stakeholder, and advocacy groups and professional organizations.
Categories: Medical

Hepatitis B Virus An Issue of Clinics in Liver Disease E Book

Hepatitis B Virus  An Issue of Clinics in Liver Disease  E Book

HBV is most prevalent viral infection worldwide.

Author: Tarek I. Hassanein

Publisher: Elsevier Health Sciences

ISBN: 9780323477055

Category: Medical

Page: 161

View: 738

HBV is most prevalent viral infection worldwide. Recent advances in HBV virology epidemiology and management are of utmost importance particularly during this time when HCV is taking the front row in discussion and research. However, there’s an increased interest in management of HBV in special populations, which is covered in this issue. The authors also explore drugs in the pipeline as well as new approaches for achieving long-term viral suppression and possibly cure.
Categories: Medical

Hepatitis B

Hepatitis B

This book reviews the mechanisms and pathogenesis of HBV, as well as discusses current and potential future treatments.

Author: Luis Rodrigo

Publisher: BoD – Books on Demand

ISBN: 9781803550060

Category: Medical

Page: 128

View: 451

Current pharmacologic therapies for chronic hepatitis B virus (HBV) infection allow viral suppression and normalization of the liver enzyme alanine aminotransferase (ALT) and prevent liver disease from progressing. The currently available antiviral therapies very rarely lead to a functional cure. Thus, the future of a cure for HBV lies in triple combination therapies with concerted action on replication inhibition, antigen reduction, and immune stimulation. This book reviews the mechanisms and pathogenesis of HBV, as well as discusses current and potential future treatments.
Categories: Medical

Hepatitis B Research Advances

Hepatitis B Research Advances

It was originally known as serum hepatitis and has caused epidemics in parts of Asia and Africa. This book presents the advances in the field.

Author: Alicia P. Willis

Publisher: Nova Publishers

ISBN: 1600216668

Category: Medical

Page: 332

View: 433

Hepatitis B is a disease of the liver caused by the Hepatitis B virus (HBV), a member of the Hepadnavirus family and one of several unrelated viral species which cause viral hepatitis. It was originally known as serum hepatitis and has caused epidemics in parts of Asia and Africa. This book presents the advances in the field.
Categories: Medical

Viral Hepatitis Chronic Hepatitis B

Viral Hepatitis  Chronic Hepatitis B

This book presents up-to-date, practically oriented information on major topics in chronic hepatitis B. The coverage encompasses epidemiology; diagnosis, including molecular methods; treatment and challenges; and the management of co ...

Author: Resat Ozaras

Publisher: Springer

ISBN: 9783319934495

Category: Medical

Page: 117

View: 818

This book presents up-to-date, practically oriented information on major topics in chronic hepatitis B. The coverage encompasses epidemiology; diagnosis, including molecular methods; treatment and challenges; and the management of co-infections. Readers will also find guidance on the invasive and non-invasive assessment of fibrosis in HBV infection and the prevention of mother-to-child transmission of HBV. Management of chronic hepatitis B in children is considered separately, and emerging drugs that hold promise for the treatment of chronic HBV infection are discussed. Chronic Hepatitis B will be of high value for general practitioners and specialists in gastroenterology, infectious diseases, and internal medicine. It will be international in scope in terms of both authorship and appeal.
Categories: Medical

Eliminating the Public Health Problem of Hepatitis B and C in the United States

Eliminating the Public Health Problem of Hepatitis B and C in the United States

Hepatitis B and C cause most cases of hepatitis in the United States and the world. The two diseases account for about a million deaths a year and 78 percent of world's hepatocellular carcinoma and more than half of all fatal cirrhosis.

Author: National Academies of Sciences, Engineering, and Medicine

Publisher: National Academies Press

ISBN: 9780309437998

Category: Medical

Page: 187

View: 676

Hepatitis B and C cause most cases of hepatitis in the United States and the world. The two diseases account for about a million deaths a year and 78 percent of world's hepatocellular carcinoma and more than half of all fatal cirrhosis. In 2013 viral hepatitis, of which hepatitis B virus (HBV) and hepatitis C virus (HCV) are the most common types, surpassed HIV and AIDS to become the seventh leading cause of death worldwide. The world now has the tools to prevent hepatitis B and cure hepatitis C. Perfect vaccination could eradicate HBV, but it would take two generations at least. In the meantime, there is no cure for the millions of people already infected. Conversely, there is no vaccine for HCV, but new direct-acting antivirals can cure 95 percent of chronic infections, though these drugs are unlikely to reach all chronically-infected people anytime soon. This report, the first of two, examines the feasibility of hepatitis B and C elimination in the United States and identifies critical success factors. The phase two report will outline a strategy for meeting the elimination goals discussed in this report.
Categories: Medical

Hepatitis B

Hepatitis B

This book presents a compilation of current research including such topics as Hepatitis B and dialysis; Hepatitis B virus infection among middle school students in South Brazil; genotyping and management of chronic Hepatitis B; the risk ...

Author: Jeffery T. Cox

Publisher: Nova Biomedical

ISBN: 1620818469

Category: Medical

Page: 188

View: 708

Hepatitis B virus (HBV) infection is a problem of global health importance and represents a significant cause of morbidity and mortality world-wide. HBV can be transmitted parenterally, sexually and perinatally. Despite progress on prophylaxis, diagnostic and treatment of HBV infection, it remains one of the major causes of chronic liver disease, cirrhosis or hepatocellular carcinoma. This book presents a compilation of current research including such topics as Hepatitis B and dialysis; Hepatitis B virus infection among middle school students in South Brazil; genotyping and management of chronic Hepatitis B; the risk assessment for Hepatitis B infection and its role in hepatocellular carcinoma; and silencing Hepatitis B virus replication with antiviral Pri-Mir shuttles generated from liver-specific Pol II promoters.
Categories: Medical