Microbial Protein Toxins

Microbial Protein Toxins

This book describes the strategies employed by protein toxins to render their pro- and eukaryotic producers a selective growth advantage over competitors.

Author: Manfred Schmitt

Publisher: Springer Science & Business Media

ISBN: 3540235620

Category: Science

Page: 237

View: 797

Since the initial establishment of Robert Koch’s postulates in the nineteenth century, microbial protein toxins have been recognized as a major factor of bacterial and fungal virulence. An increasing number of proteins produced and secreted by various bacteria, yeasts and plants are extremely toxic and most of them developed remarkably "intelligent" strategies to enter, to penetrate and to finally kill a eukaryotic target cell by modifying or blocking essential cellular components. This book describes the strategies employed by protein toxins to render their pro- and eukaryotic producers a selective growth advantage over competitors. In providing an up-to-date overview on the mode of protein toxin actions, it accommodates biomedically and biologically relevant toxin model systems. As a result, it significantly broadens our perspective on biochemical architecture and molecular ploy behind the lethal principles of pro- and eukaryotic toxins.
Categories: Science

The Comprehensive Sourcebook of Bacterial Protein Toxins

The Comprehensive Sourcebook of Bacterial Protein Toxins

This book contains chapters devoted to individual toxins, as well as chapters that consider the different applications of these toxins.

Author: Joseph E. Alouf

Publisher: Academic Press

ISBN: 9780128005897

Category: Science

Page: 1200

View: 120

The Comprehensive Sourcebook of Bacterial Protein Toxins 4th Edition, contains chapters written by internationally known and well-respected specialists. This book contains chapters devoted to individual toxins, as well as chapters that consider the different applications of these toxins. Considerable progress has been made in understanding the structure, function, interaction and trafficking into cells, as well as mechanism of action of toxins. Bacterial toxins are involved in the pathogenesis of many bacteria, some of which are responsible for severe diseases in human and animals, but can also be used as tools in cell biology to dissect cellular processes or used as therapeutic agents. Novel recombinant toxins are already proposed in the treatment of some diseases, as well as new vaccines. Alternatively, certain toxins are also considered as biological weapons or bioterrorism threats. Given the multifaceted aspects of toxin research and the multidisciplinary approaches adopted, toxins are of great interest in many scientific areas from microbiology, virology, cell biology to biochemistry and protein structure. This new edition is written with a multidisciplinary audience in mind and contains 5 new chapters that reflect the latest research in this area. Other chapters have been combined, deleted and fully revised as necessary to deliver relevant and valuable content. Descriptions of relevant toxins as well as representative toxins of the main bacterial toxin families to allow for a better comparison between them. Focused chapters on toxin applications and common properties or general features of toxins.
Categories: Science

Microbial Protein Toxins

Microbial Protein Toxins

This book describes the strategies employed by protein toxins to render their pro- and eukaryotic producers a selective growth advantage over competitors.

Author: Manfred Schmitt

Publisher: Springer

ISBN: 3540804714

Category: Science

Page: 237

View: 825

Since the initial establishment of Robert Koch’s postulates in the nineteenth century, microbial protein toxins have been recognized as a major factor of bacterial and fungal virulence. An increasing number of proteins produced and secreted by various bacteria, yeasts and plants are extremely toxic and most of them developed remarkably "intelligent" strategies to enter, to penetrate and to finally kill a eukaryotic target cell by modifying or blocking essential cellular components. This book describes the strategies employed by protein toxins to render their pro- and eukaryotic producers a selective growth advantage over competitors. In providing an up-to-date overview on the mode of protein toxin actions, it accommodates biomedically and biologically relevant toxin model systems. As a result, it significantly broadens our perspective on biochemical architecture and molecular ploy behind the lethal principles of pro- and eukaryotic toxins.
Categories: Science

Bacterial Protein Toxins V2A

Bacterial Protein Toxins V2A

The book's 10 chapters discuss the following: botulinum toxin; tetanus toxin; Clostridium perfringens toxins types A, B, C, D, and E; cholera toxins; the exotoxin of Shigella dysenteriae; protein toxins from Bordetella pertussis; Salmonella ...

Author: Solomon Kadis

Publisher: Elsevier

ISBN: 9780323150514

Category: Medical

Page: 432

View: 153

Microbial Toxins, A Comprehensive Treatise, Volume IIA: Bacterial Protein Toxins provides a comprehensive discussion of various aspects of bacterial toxins. The book's 10 chapters discuss the following: botulinum toxin; tetanus toxin; Clostridium perfringens toxins types A, B, C, D, and E; cholera toxins; the exotoxin of Shigella dysenteriae; protein toxins from Bordetella pertussis; Salmonella typhimurium and Escherichia coli neurotoxins; toxins of Proteus mirabilis; and Listeria monocytogenes toxin. Each chapter covers the nature of the toxin, toxin production and purification, and mode of action.
Categories: Medical

Bacterial Protein Toxins

Bacterial Protein Toxins

Bacterial Protein Toxins V3

Author: Thomas C. Montie

Publisher: Elsevier

ISBN: 9780323163224

Category: Science

Page: 568

View: 655

Bacterial Protein Toxins V3
Categories: Science

Bacterial Toxins

Bacterial Toxins

The present volume Bacterial Toxins: Methods and Pro- cols, is intended to fill this gap. Bacterial Toxins: Methods and Protocols consists of two sections: one on protein toxins (15 chapters) and one on endotoxins (5 chapters).

Author: Otto Holst

Publisher: Springer Science & Business Media

ISBN: 9781592590520

Category: Medical

Page: 379

View: 473

The interest of investigators across a broad spectrum of scientific dis- plines has been steadily stimulated by the field of bacterial toxin research, an area that makes use of a large variety of biological, chemical, physicochemical, and medically oriented approaches. Researchers studying bacterial toxins need to be acquainted with all these disciplines in order to work effectively in the field. To date, there has been no published collection offering detailed descr- tions of the techniques and methods needed by researchers operating across the field’sdiverse areas. The present volume Bacterial Toxins: Methods and Pro- cols, is intended to fill this gap. Bacterial Toxins: Methods and Protocols consists of two sections: one on protein toxins (15 chapters) and one on endotoxins (5 chapters). Each s- tion is introduced by an overview article (Chapters 1 and 16). The protocols collected represent state-of-the-art techniques that each have high impact on future bacterial toxin research. All methods are described by authors who have regularly been using the protocol in their own laboratories. Included in each chapter is a brief introduction to the method being described.
Categories: Medical

Microbial Toxins

Microbial Toxins

Author: Samuel J. Ajl

Publisher:

ISBN: LCCN:78084247

Category:

Page: 412

View: 783

Categories:

Bacterial Protein Toxins

Bacterial Protein Toxins

Band 1, 2A, 2B, 3.

Author: Thomas C. Montie

Publisher:

ISBN: 0120465035

Category: Microorganisms

Page: 548

View: 475

Band 1, 2A, 2B, 3.
Categories: Microorganisms

Microbial Toxins

Microbial Toxins

Author: Alex Ciegler

Publisher:

ISBN: OCLC:502596473

Category: Bacterial toxins

Page: 517

View: 332

Categories: Bacterial toxins