Author: María-Teresa Pérez-GraciaPublish On: 2021-05-11
This is mainly due to the appearance of antibiotic-resistant strains, inefficient diagnostic methods and poor sexual education.
Author: María-Teresa Pérez-Gracia
Publisher: MDPI
ISBN: 9783036507903
Category: Medical
Page: 102
View: 456
Gonorrhea is a sexually transmitted infection caused by the obligate human pathogen“Neisseria gonorrhoeae”. This Gram-negative diplococcus is highly infective due to its virulence factors: pili, Por proteins, Opa proteins, Rmp proteins, lipooligosaccharides and IgA protease. Despite existing guidelines for its treatment, the incidence of the disease follows an increasing trend worldwide. This is mainly due to the appearance of antibiotic-resistant strains, inefficient diagnostic methods and poor sexual education. Without an effective vaccine available, the key priorities for the control of the disease include sexual education, contact notification, epidemiological surveillance, diagnosis and effective antibiotic treatment. This Special Issue focuses on some of these important issuesm such as the molecular mechanisms of the disease, diagnostic tests and different treatment strategies used to combat gonorrhea.
This is mainly due to the appearance of antibiotic-resistant strains, inefficient diagnostic methods and poor sexual education.
Author: María-Teresa Pérez-Gracia
Publisher:
ISBN: 3036507914
Category:
Page: 102
View: 832
Gonorrhea is a sexually transmitted infection caused by the obligate human pathogen“Neisseria gonorrhoeae”. This Gram-negative diplococcus is highly infective due to its virulence factors: pili, Por proteins, Opa proteins, Rmp proteins, lipooligosaccharides and IgA protease. Despite existing guidelines for its treatment, the incidence of the disease follows an increasing trend worldwide. This is mainly due to the appearance of antibiotic-resistant strains, inefficient diagnostic methods and poor sexual education. Without an effective vaccine available, the key priorities for the control of the disease include sexual education, contact notification, epidemiological surveillance, diagnosis and effective antibiotic treatment. This Special Issue focuses on some of these important issuesm such as the molecular mechanisms of the disease, diagnostic tests and different treatment strategies used to combat gonorrhea.
Rarely, infection with N. gonorrhoeae disseminates leading to septic arthritis and skin manifestations. Antibiotic resistance in N. gonorrhoeae strains is on the rise worldwide and effective treatment options have become limited.
Case Studies in Infectious Disease: Neisseria gonorrhoeae presents the natural history of this infection from point of entry of the pathogen through pathogenesis, clinical presentation, diagnosis, and treatment.
Author: Peter Lydyard
Publisher: Garland Science
ISBN: 9781136986345
Category: Medical
Page: 608
View: 514
Case Studies in Infectious Disease: Neisseria gonorrhoeae presents the natural history of this infection from point of entry of the pathogen through pathogenesis, clinical presentation, diagnosis, and treatment. A set of core questions explores the nature, causation, host response, manifestations, and management of this infectious process. This case also includes summary bullet points, questions and answers, and references.
Author: Pan American Pan American Health OrganizationPublish On: 2020-06-18
Prevention, early diagnosis, and effective treatment are essential for the control and elimination of Neisseria gonorrhoeae as a public health problem.
Author: Pan American Pan American Health Organization
Publisher: Pan American Health Organization
ISBN: 9275122377
Category:
Page: 38
View: 988
Prevention, early diagnosis, and effective treatment are essential for the control and elimination of Neisseria gonorrhoeae as a public health problem. Currently, in Latin America and the Caribbean, treatment for gonorrhea infection is largely empiric and based on clinical diagnosis. In the Americas, the high burden of new N. gonorrhoeae infections (estimated at 11 million new cases a year), the complexity of the disease epidemiology, and in many countries the limited resources, make it difficult to fully understand the burden of disease and the burden of antimicrobial resistance (AMR) in N. gonorrhoeae. PAHO has developed this document to facilitate the navigation of available guidance and recommendations for N. gonorrhoeae AMR surveillance by public health and health care professionals, at the national and subnational levels, involved in designing, implementing, and/or strengthening AMR surveillance of N. gonorrhoeae and overall surveillance of sexually transmitted infections. This document aims to consolidate guidance on AMR surveillance for N. gonorrhoeae from documents published by WHO and PAHO, and strives to assemble relevant information in a summarized manner to help countries in strengthening and/or developing AMR surveillance systems for N. gonorrhoeae.
"Since publication of CDC's 1993 guidelines (CDC. Recommendations for the prevention and management of Chlamydia trachomatis infections, 1993. MMWR 1993;42[No.
Author: Robert E. Johnson
Publisher:
ISBN: OCLC:496283524
Category: Gonorrhea
Page: 40
View: 788
"Since publication of CDC's 1993 guidelines (CDC. Recommendations for the prevention and management of Chlamydia trachomatis infections, 1993. MMWR 1993;42[No. RR-12]:1--39), nucleic acid amplification tests (NAATs) have been introduced as critical new tools to diagnose and treat C. trachomatis and Neisseria gonorrhoeae infections. NAATs for C. trachomatis are substantially more sensitive than previous tests. When using a NAAT, any sacrifice in performance when urine is substituted for a traditional swab specimen is limited, thus reducing dependence on invasive procedures and expanding the venues where specimens can be obtained. NAATs can also detect both C. trachomatis and N. gonorrhoeae organisms in the same specimen. However, NAATs are usually more expensive than previous tests, making test performance from an economic perspective a key consideration. This report updates the 1993 guidelines for selecting laboratory tests for C. trachomatis with an emphasis on screening men and women in the United States. (In this report, screening refers to testing persons in the absence of symptoms or signs indicating C. trachomatis or N. gonorrhoeae infection.) In addition, these guidelines consider tests from an economic perspective and expand the previous guidelines to address detection of N. gonorrhoeae as well as C. trachomatis infections. Because of the increased cost of NAATs, certain laboratories are modifying manufacturers' procedures to improve test sensitivity without incurring the full cost associated with screening with a NAAT. Such approaches addressed in these guidelines are pooling of specimens before testing with a NAAT and additional testing of specimens whose non-NAAT test result is within a gray zone. This report also addresses the need for additional testing after a positive screening test to improve the specificity of a final diagnosis. To prepare these guidelines, CDC staff identified pertinent concerns, compiled the related literature published during 1990 or later, prepared tables of evidence, and drafted recommendations. Consultants, selected for their expertise or disciplinary and organizational affiliations, reviewed the draft recommendations. These final guidelines are the recommendations of CDC staff who considered contributions from scientific consultants. These guidelines are intended for laboratorians, clinicians, and managers who must choose among the multiple available tests, establish standard operating procedures for collecting and processing specimens, interpret test results for laboratory reporting, and counsel and treat patients. " - p. 1
93 role in serotype specificity, 121 Outer membrane components in serum-sensitive and -resistant N. gonorrhoeae. 139 Outer membrane protein of N. gonorrhoeae association with disseminated gonococcal infection.
Author: Dawn L. (Dawn Lynn) WuskynykPublish On: 2004
Descriptive statistics and frequency distributions were completed for each variable to become familiar with the data. Since this is a cohort study, incidence rates and measures of association, such as the relative risk, were completed.
Author: Dawn L. (Dawn Lynn) Wuskynyk
Publisher: Library and Archives Canada = Bibliothèque et Archives Canada
ISBN: 0612972356
Category:
Page: 242
View: 504
The association between being infected with the sexually transmitted infections (STIs), Chlamydia trachomatis or Neisseria gonorrhoeae and developing pelvic inflammatory disease (PID) is supported in the literature. Research also demonstrates an association between repeat infections with chlamydia or gonorrhea and acquiring PID. While there is some information from Canada on this topic, the majority of the research is from the United States and abroad. Additionally, there are few studies that have been able to examine the risk of acquiring PID utilizing a prospective study design. The purpose of this study is to identify the risk of women in Manitoba acquiring PID from one or more episodes of genital chlamydia or gonorrhea. The length of time following a genital chlamydial or gonococcal infection where PID develops is explored. Obtaining information on the risks of acquiring PID, among women in Manitoba with genital chlamydia or gonorrhea, has important policy implications such as early detection and screening of STIs, treatment procedures, partner notification and contact tracing. A surveillance system framework was used to guide the study. The data were acquired by linking administrative databases from Cadham Provincial Laboratory and Manitoba Health. Three cohorts of women were chosen, based on their history of testing positive or negative for STIs. Quantitative data analysis was completed through the use of the Statistical Analysis Software (SAS) program. Descriptive statistics and frequency distributions were completed for each variable to become familiar with the data. Since this is a cohort study, incidence rates and measures of association, such as the relative risk, were completed. Tests of statistical significance were also calculated. Study findings indicate that l5 - 24 year old women, in Manitoba with documented infections of genital...
Descriptive statistics and frequency distributions were completed for each variable to become familiar with the data. Since this is a cohort study, incidence rates and measures of association, such as the relative risk, were completed.
Author: Dawn L. Wuskynyk
Publisher:
ISBN: OCLC:855299735
Category:
Page: 242
View: 743
The association between being infected with the sexually transmitted infections (STIs), Chlamydia trachomatis or Neisseria gonorrhoeae and developing pelvic inflammatory disease (PID) is supported in the literature. Research also demonstrates an association between repeat infections with chlamydia or gonorrhea and acquiring PID. While there is some information from Canada on this topic, the majority of the research is from the United States and abroad. Additionally, there are few studies that have been able to examine the risk of acquiring PID utilizing a prospective study design. The purpose of this study is to identify the risk of women in Manitoba acquiring PID from one or more episodes of genital chlamydia or gonorrhea. The length of time following a genital chlamydial or gonococcal infection where PID develops is explored. Obtaining information on the risks of acquiring PID, among women in Manitoba with genital chlamydia or gonorrhea, has important policy implications such as early detection and screening of STIs, treatment procedures, partner notification and contact tracing. A surveillance system framework was used to guide the study. The data were acquired by linking administrative databases from Cadham Provincial Laboratory and Manitoba Health. Three cohorts of women were chosen, based on their history of testing positive or negative for STIs. Quantitative data analysis was completed through the use of the Statistical Analysis Software (SAS) program. Descriptive statistics and frequency distributions were completed for each variable to become familiar with the data. Since this is a cohort study, incidence rates and measures of association, such as the relative risk, were completed. Tests of statistical significance were also calculated. Study findings indicate that l5 - 24 year old women, in Manitoba with documented infections of genital...