New Trends in Radiopharmaceutical Synthesis Quality Assurance and Regulatory Control

New Trends in Radiopharmaceutical Synthesis  Quality Assurance  and Regulatory Control

, Houston, Texas, USA Harold A. O'Brien, Jr. Los Alamos National Laboratory, Los Alamos, New Mexico, USA Joseph R. Peterson Dept. of Chemistry, University of Tennessee, Knoxville, Tennessee, USA Hernan Vera Ruiz International Atomic Energy ...

Author: Ali M. Emran

Publisher: Springer Science & Business Media

ISBN: 9781489906267

Category: Medical

Page: 520

View: 689

Marking the 200th National Meeting of the American Chemical Society, The Division of Nuclear Chemistry and Technology hosted a group of about 90 scientists from 15 different countries to discuss the new trends in radiopharmaceutical synthesis, quality assurance and regulatory control. This event took place in Washington, D.C. on August 27-30, 1990. When I first suggested the idea for this symposium, a group of scientists who pioneered the proposed topics offered their help to organize and run such a big task with me. Their names are listed here in appreciation. Thomas E. Boothe Cyclotron Facility, Mt. Sinai Medical Center, Miami Beach, Florida, USA Robert F. Dannals Division of Nuclear Medicine, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA Anthony L. Feliu Julich Nuclear Research Center, Julich, Germany Joanna S. Fowler Chemistry Department, Brookhaven National Laboratory, Upton, New York, USA George W. Kabalka Department of Chemistry, University of Tennessee, Knoxville, Tennessee, USA Hank F. Kung Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA James F. Lamb Imagents, Inc., Houston, Texas, USA Harold A. O'Brien, Jr. Los Alamos National Laboratory, Los Alamos, New Mexico, USA Joseph R. Peterson Dept. of Chemistry, University of Tennessee, Knoxville, Tennessee, USA Hernan Vera Ruiz International Atomic Energy Agency, Vienna, Austria Roy S. Tilbury University of Texas, M. D. Anderson Cancer Center, Houston, Texas, USA In addition, a number of distinguished colleagues have participated in the process of reviewing the manuscripts presented in this volume. Their effort is sincerely acknowledged.
Categories: Medical

Current Catalog

Current Catalog

9302967 HISTORY UNITED STATES NURSES ' INSTRUCTION Quality assurance of radiopharmaceuticals -- specifications and ... 9300349 TRENDS UNITED STATES AFRICA CONGRESSES African Workshop on Management of Blood Transfusion Services ( 1990 ...

Author: National Library of Medicine (U.S.)

Publisher:

ISBN: UOM:39015074107668

Category: Medicine

Page:

View: 205

First multi-year cumulation covers six years: 1965-70.
Categories: Medicine

Chemists Views of Imaging Centers

Chemists    Views of Imaging Centers

... and Quality Assurance, in: radiopharmaceutical synthesis, quality assurance and regulatory control, A.M. Emran, ed. ... 1991, Radiopharmaceutical production for PET: quality assurance practice, experience and issues, in: "New trends ...

Author: Ali M. Emran

Publisher: Springer Science & Business Media

ISBN: 9781475796704

Category: Medical

Page: 538

View: 995

To continue the support for the growing trend of chemistry involvement in nuclear medicine, the Division of Nuclear Chemistry and Technology (DNCT) of the American Chemical Society (ACS) planned for a symposium to cover this aspect. This was expressed in arequest to me, as a member of the Program Committee, to organize a symposium on topics related to nuclear and radiochemistry applications to nuclear medicine. Realizing the growing interest in imaging, specially with positron emitting radioisotopes, I invited several colleagues to study with me the idea of imaging centers and the involvement of chemists in their structure and function. The formulated Organizing Committee supported this idea which evolved in proposing an extended international symposium to be held in conjunction with the 206th ACS National meeting in Chicago, Illinois, U. S. A. on August 22-27, 1993. The following are the members of the Organizing Committee: Jorge R. Barrio, Ph. D. Thomas E. Boothe, Ph. D. J. Robert Dahl, Ph. D. Robert F. Dannals, Ph. D. Bruce R. Erdal, Ph. D. Mark M. Goodman, Ph. D. George W. Kabalka, Ph. D. James F. Lamb, Ph. D. Ronald G. Manning, Ph. D. Henry C. Padgett, Ph. D. Roy S. Tilbury, Ph. D. Steven W. Yates, Ph. D. and Ali M. Emran, Ph. D.
Categories: Medical

Handbook of Radiopharmaceuticals

Handbook of Radiopharmaceuticals

Lodi, F. and Boschi, S. (2016). quality control of pet radiopharmaceuticals. In: Basic Science of PET Imaging (ed. ... In: New Trends in Radiopharmaceutical Synthesis, Quality Assurance, and Regulatory Control (ed. A.M. Emran), 355–370.

Author: Michael R. Kilbourn

Publisher: John Wiley & Sons

ISBN: 9781119500544

Category: Science

Page: 768

View: 662

The thoroughly updated new edition of the authoritative reference in Radiopharmaceutical Sciences The second edition of Handbook of Radiopharmaceuticals is a comprehensive review of the field, presenting up-to-date coverage of central topics such as radionuclide production, synthetic methodology, radiopharmaceutical development and regulations, and a wide range of practical applications. A valuable reference work for those new to the Radiopharmaceutical Sciences and experienced professionals alike, this volume explores the latest concepts and issues involving both targeted diagnostic and therapeutic radiopharmaceuticals. Contributions from a team of experts from across sub-disciplines provide readers with an immersive examination of radiochemistry, nuclear medicine, molecular imaging, and more. Since the first edition of the Handbook was published, Nuclear Medicine and Radiopharmaceutical Sciences have undergone major changes. New radiopharmaceuticals for diagnosis and therapy have been approved by the FDA, the number of clinical PET and SPECT scans have increased significantly, and advances in Artificial Intelligence have dramatically improved research techniques. This fully revised edition reflects the current state of the field and features substantially updated and expanded content. New chapters cover topics including current Good Manufacturing Practice (cGMP), regulatory oversight, novel approaches to quality control—ensuring that readers are informed of the exciting developments of recent years. This important resource: Features extensive new and revised content throughout Covers key areas of application for diagnosis and therapy in oncology, neurology, and cardiology Emphasizes the multidisciplinary nature of Radiopharmaceutical Sciences Discusses how drug companies are using modern radiopharmaceutical imaging techniques to support drug discovery Examines current and emerging applications of Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) Edited by recognized experts in radiochemistry and PET imaging, Handbook of Radiopharmaceuticals: Radiochemistry and Applications, 2nd Edition is an indispensable reference for post-doctoral fellows, research scientists, and professionals in the pharmaceutical industry, and for academics, graduate students, and newcomers in the field of radiopharmaceuticals.
Categories: Science

Handbook of Radiopharmaceuticals

Handbook of Radiopharmaceuticals

Ruth TJ , Adam MJ , Morris D , Jivan S and Tyldesley S ( 1991b ) The use of transducers for automated radiopharmaceutical synthesis procedures . In New Trends in Radiopharmaceutical Synthesis , Quality Assurance , and Regulatory Control ...

Author: Michael J. Welch

Publisher: John Wiley & Sons

ISBN: 0471495603

Category: Medical

Page: 862

View: 594

A comprehensive, authoritative and up-to-date reference for the newcomer to radiopharmaceuticals and those already in the field. Radiopharmaceuticals are used to detect and characterise disease processes, or normal biological function, in living cells, animals or humans. Used as tracer molecules, they map the distribution, uptake and metabolism of the molecule in clinical studies, basic research or applied research. The area of radiopharmaceuticals is expanding rapidly. The number of PET centers in the world is increasing at 20% per year, and many drug companies are utilising PET and other forms of radiopharmaceutical imaging to evaluate products. * Readers will find coverage on a number of important topics such as radionuclide production, PET and drug development, and regulations * Explains how to use radiopharmaceuticals for the diagnosis and therapy of cancer and other diseases * The editors and a majority of the contributors are from the United States
Categories: Medical

Radiopharmaceuticals for Therapy

Radiopharmaceuticals for Therapy

Dvorakova Z, Henkelmann R, Lin X, Türler A, Gerstenberg H. Production of 177Lu at the new research reactor FRM-II: irradiation yield of ... In: New trends in radiopharmaceutical synthesis, quality assurance, and regulatory control.

Author: F. F. (Russ) Knapp

Publisher: Springer

ISBN: 9788132226079

Category: Medical

Page: 347

View: 338

This book provides detailed information on therapeutic radiopharmaceuticals and discusses emerging technologies which have potential for broad clinical implementation. Recent advances in molecular biology, radiopharmaceutical chemistry and radioisotope production have stimulated a new era for the use of radiopharmaceuticals for targeted radionuclide therapy (TRT). Emerging clinical trials include use of peptides and monoclonal antibodies radiolabeled with therapeutic radionuclides for cancer therapy. In addition, small molecules are used for the treatment of chronic diseases such as metastatic bone pain palliation and radiation synovectomy of inflammatory joints. In the interventional arena, therapy of primary and metastatic liver cancer and arterial restenosis following angioplasty of both the coronary and peripheral arteries are being explored. Reactor and accelerator production of therapeutic radioisotopes is also integrated into these discussions. The development and use of radiopharmaceutical targeting characteristics required for treatment of specific disease processes and how these are implemented for radiopharmaceutical design strategies are also described. Radiopharmaceuticals for Therapy will benefit audiences in nuclear medicine and radionuclide therapy and will thus prove an invaluable source of up-to-date information for students, radiopharmaceutical scientists and professionals working in the radiopharmacy and nuclear medicine specialties.
Categories: Medical

National Library of Medicine Current Catalog

National Library of Medicine Current Catalog

Division of Biochemical Technology American Chemical Society International Symposium on Radiopharmaceutical Synthesis , Quality Assurance , and Regulatory Control ( 1990 : Washington , D.C. ) . New trends ...

Author: National Library of Medicine (U.S.)

Publisher:

ISBN: MINN:31951D01092867R

Category: Medicine

Page:

View: 796

Categories: Medicine

Comprehensive Handbook of Iodine

Comprehensive Handbook of Iodine

Kabalka, G.W. and Goodman, M.M. (1991). Synthesis of radiopharmaceuticals via organoboranes. In: (ed. A.M. Emram), New Trends in Radiopharmaceutical Synthesis, Quality Assurance and Regulatory Control. Plenum Press, New York, NY.

Author: Victor R. Preedy

Publisher: Academic Press

ISBN: 0080920861

Category: Technology & Engineering

Page: 1334

View: 135

Over two billion people worldwide are at risk for the spectrum of disorders known as "The Iodine Deficiency Disorders." 1-10% will suffer cretinism; 5-30% will have some sort of brain damage or neurological impairment and 30-70% will be hypothyroid. The causes of iodine deficiencies can be considered from both simplistic and more complex perspectives: From the leaching of iodine from soil resulting in crops with low iodine content to malnutrition resulting in impaired iodine absorption. Poor dietary diversification and impoverished socio-economic development can also lead to iodine deficiencies. Although it is possible to diagnose and treat deficiencies, there is still an ongoing dialogue regarding the detailed molecular pathology of iodine homeostatis, how hypothyroidism impacts the body tissues, and efficient diagnosis and treatment of the Iodine Deficiency Disorders. This Handbook provides a resource of information on the various pathways and processes based on different countries or diseases. Because there is a constant flow of new information on iodine and related disorders, the goal of this Handbook is to provide a base of scientific information upon which additional knowledge can be applied. Provides important information on one of the most common micro-nutrient deficiencies in the world, the most important "single nutrient-multiple consequences" paradigm today Includes information on iodine-related diseases, including those that are common, preventable and treatable Provides insight from a broad perspective of viewpoints -- from subcellular transports to economic impact
Categories: Technology & Engineering

Basic Sciences of Nuclear Medicine

Basic Sciences of Nuclear Medicine

Flanagan RJ. The synthesis of halogenated radiopharmaceuticals using organomercurials. In: Emran AM, editor. New trends in radiopharmaceutical synthesis quality assurance and regulatory control. New York: Plenum Press; 1991. p. 279–88.

Author: Magdy M. Khalil

Publisher: Springer Nature

ISBN: 9783030652456

Category: Medical

Page: 571

View: 648

This book provides comprehensive and detailed information on the scientific bases of nuclear medicine, addressing a wide variety of topics and explaining the concepts that underlie many of the investigations and procedures performed in the field. The book is divided into six sections that cover the physics and chemistry of nuclear medicine besides associated quality assurance/quality control procedures; dosimetry and radiation biology; SPECT and PET imaging instrumentation plus CT imaging technology in hybrid modalities; data analysis including image processing, reconstruction, radiomics, image degrading correction techniques, along with image quantitation and kinetic modeling. Within these sections, particular attention is paid to recent developments and the advances in knowledge that have taken place since release of the first edition in 2011. Several entirely new chapters have been included and the remaining chapters, thoroughly updated. Innovations in the ever-expanding field of nuclear medicine are predominantly due to integration of the basic sciences with complex technological advances. This excellently illustrated book on the subject will be of interest to not only nuclear medicine physicists and physicians but also clinical scientists, radiologists, radiopharmacists, medical students and technologists.
Categories: Medical