Assessment of the role of nickel in causing hand dermatitis has been complicated. It is not uncommon to find nickel allergy on patch testing, but it is difficult to determine whether this is of relevance for hand eczema or simply a ...
Author: Jennifer K Chen
This volume opens by providing a comprehensive overview of the use and regulation of metals in our society, metal properties, and available testing methodologies. Common and uncommon metal allergens and sources of exposure are then reviewed in depth, detailing allergic responses and paying special consideration to select patient populations. In the general population, the prevalence of metal allergy is high. Environmental sources of metal exposure include jewelry, clothing, electronic devices, coins, leather, diet, and occupational exposure. Metal allergy may result in allergic contact dermatitis and systemic contact dermatitis, as well as several less common manifestations. Further, metal allergy has been associated with device failure and/or dermatitis following implantation of medical devices and dental implants. As metals are ubiquitous, this book will be indispensable for a wide range of clinicians and investigators. This handy reference will meet the needs of all health professionals and investigators who are interested in metal allergy and its diagnosis and management.
Provides basic consumer health information for teens about allergies, including facts about treating and preventing allergic reactions and complications, and tips for coping with allergies at home and school. Includes index and resource information.
Bezzon, O.L., Allergic sensitivity to several base metals: a clinical report, J. Prosth. Dent., 69,243–244, 1993. Blanco-Dalmau, L., Carrasquillo-Alberty, H., and Silva-Parra, J., A study of nickel allergy, J. Prosth.
Author: Jurij J. Hostynek
Publisher: CRC Press
First published 2002, Allergic contact dermatitis from nickel is a continuing and increasing health problem. Nickel dermatitis may occur in sensitized individuals following contact with nickel-containing items such as jewelry, zippers, buttons, and other objects; by nickel leaching from implants and prostheses; and following occupational exposures. Although the most common of the health effects associated with exposure to nickel, the skin penetration of nickel and its compounds is poorly understood. Nickel and the Skin: Absorption, Immunology, Epidemiology, and Metallurgy gives an extensive, updated review of major topics and new topics, and covers material progress in the field of nickel hypersensitivity. Its content complements the mandate of NiPERA, the Nickel Producers Environmental Research Association, which is to promote the health and safety of those exposed to nickel or nickel containing products in the workplace and general environment. Many books on the toxicology of metals discuss nickel and its alloys in general terms. This one provides you with in-depth information on the causes, diagnosis, prognosis, and prevention, all in one source. Nickel and the Skin: Absorption, Immunology, Epidemiology, and Metallurgy provides a guide to the evaluation and treatment of what has become the most common cause of allergic contact dermatitis.
Menné T , Borgan Ø , Green A. Nickel allergy and hand dermatitis in a stratified sample of the Danish female population : An epidemiological study including a statistic appendix . Acta Derm Venereol ( Stockh ) 1982 : 62 : 35-41 98.
One female patient, known to be allergic to costume jewellery, developed edema and eczema of the eyelids after using a new blue eyeshadow that proved to contain 16.9 μg nickel/g (ppm). The patch test with the product was negative, ...
Author: Anton C. de Groot
Publisher: CRC Press
Monographs in Contact Allergy, Volume 1: Non-Fragrance Allergens in Cosmetics (Part 1 and Part 2) is the first 2-part volume in an exciting series on contact allergy. It presents over 500 natural or synthetic chemicals and compounds which have caused allergic contact dermatitis in cosmetic products. Included here are INCI names, synonyms, description/definition, CAS and EU numbers, chemical class, function in cosmetics, molecular formula, structural formula and advice on patch tests. A full literature review is given of patch testing in patients, case reports of cosmetic allergic contact dermatitis, irritant contact dermatitis, photosensitivity, immediate contact reactions and systemic side effects. This text is suitable for anyone with an interest in contact allergy, from university students to professionals, and all readers will find this informative and detailed series an invaluable resource. Key Features: Monographs of all known non-fragrance chemicals and substances which have caused allergic contact dermatitis from their presence in cosmetic products Provides lists of all functional groups (such as antioxidants, preservatives, artificial nail building, emollients, hair dyeing, hair colorants) in both the EU and US formats and all chemicals in these groups which have caused cosmetic allergy Presents an alphabetical list of all synonyms indicating their INCI names Reported cross-reactions, pseudo-cross-reactions and co-reactions, patch test sensitization and presence in cosmetic products (including data from FDA’s Voluntary Cosmetic Registration Program) and chemical analyses are discussed Covers an extensive amount of information to benefit dermatologists, allergists, and non-medical professionals involved with the research, development and marketing of cosmetic products
Veien et al.67 challenged nickel - allergic patients with eczema other than vesicular hand eczema and saw flares of the ... procedure the following questions arise : • Is recurrent vesicular hand eczema associated with nickel allergy ?
Author: Torkil Menne
Publisher: CRC Press
Exogenous Dermatoses presents a collection of comprehensive essays written by experts scientifically active in exogenous dermatoses research. Main areas covered include basic biological mechanisms, diagnostic methods, experimental investigations, and clinical aspects. The book will be an important source of reference for clinical and experimental dermatologists and scientists working with skin immunology and toxicology. It will also provide important information for cosmetic and pharmaceutical research.
V. PREVENTION A. Preventive Strategies The major adverse health effects due to nickel are nickel allergy , as reviewed in this volume , and cancer of the respiratory tract . Sensitization is due to cutaneous exposure to soluble nickel ...
Author: Howard I. Maibach
Publisher: CRC Press
This publication serves as a guide to medical doctors and dentists in the evaluation and management of problems related to nickel allergy. The chemistry, analysis, and monitoring of nickel is explored. Recent advances in the immunology of nickel are dis-cussed. Additionally, sensitization assays for both humans and animals are presented. The clinical, genetic, and epidemiologic as-pects of nickel sensitization and nickel dermatitis are explained. Social and demographic aspects of nickel contact allergy are dis-cussed, as well as the topic of the nickel dermatitis as a pre-ventable health problem.
ing the cellular uptake by peripheral blood T cells between nickel-allergic and control subjects , ... Production of migration inhibitory factors for leucocytes has been used for diagnosis of nickel allergy in vitro .
There are five main subject areas in this volume in the series on medicinal chemistry. The first is a review of the understanding of Alzheimer's disease and the development of drugs for its treatment; the second, looking at recent efforts in modifying a naturally occuring anticancer (campothecin) for chemotherapy; the third covers the problem of getting a drug to a specific site within the context of phosphates and phosphonates; a survey of sterilization using aldehydes for the destruction of microbes both inside and outside the human body is reviewed in the fourth; and the last chapter is an account of the progress made in the biologically active enantiomer for complex synthetic asymmetric drug molecules.
In addition, it has been suggested that disorders such as allergic vasculitis and polymorphic erythema can become chronic after ingestion of nickel (8). All these different clinical pictures can be defined as "systemic contact- type ...
8.5 Allergies 8.5.1 Mechanisms As far as is known, metal ions cannot act as allergens themselves [49, 114]. ... The frequency of nickel allergies in a group of 14–18-year-old adolescents was 30% among girls, 3% among boys, and 31% among ...
Author: Gottfried Schmalz
Publisher: Springer Science & Business Media
This book provides a comprehensive and scientifically based overview of the biocompatibility of dental materials. Up-to-date concepts of biocompatibility assessment are presented, as well as information on almost all material groups used in daily dentistry practice. Furthermore, special topics of clinical relevance (e.g,, environmental and occupational hazards and the diagnosis of adverse effects) are covered. The book will: improve the reader’s ability to critically analyze information provided by manufacturers supply a better understanding of the biocompatibility of single material groups, which will help the reader choose the most appropriate materials for any given patient and thus prevent adverse effects from developing provide insights on how to conduct objective, matter-of-fact discussions with patients about the materials to be used in dental procedures advise readers, through the use of well-documented concepts, on how to treat patients who claim adverse effects from dental materials feature clinical photographs that will serve as a reference when analyzing clinical symptoms, such as oral mucosa reactions.