This is a must-have reference for all those interested in salivary biomarkers across the bioscience and biomedical fields.
Author: Zohaib Khurshid
Publisher: Academic Press
Salivary Biomarkers for Oral and Systemic Diseases contains contributions from a number of experts those are highly regarded scientists and clinicians. This book offers unique insights into the science of biomarkers in oral diseases and how to use biomarkers to help in the diagnosis of oral diseases and systemic diseases. Salivary Biomarkers for Oral Diseases focuses on all oral fluids, such as GCF, peri-implant fluid, and whole mouth saliva, and outlines the practical importance of the use of other biological samples from the oral cavity. This is a must-have reference for all those interested in salivary biomarkers across the bioscience and biomedical fields. Includes a wide range of topics related to the field of omics, molecular biology and diagnosing oral diseases Outlines the fundamentals on biomarkers role in oral biology and how protein biomarkers help to diagnose oral diseases Includes coverage of biosensor development and point of care technology role in future dentistry
Author: Charles F. StreckfusPublish On: 2015-02-03
Advances in Salivary Diagnostics will be an informative and stimulating reference for both practitioners and students. This book reviews the progress made in salivary diagnostics and identifies the likely direction of future endeavors.
Author: Charles F. Streckfus
This book reviews the progress made in salivary diagnostics during the past two decades and identifies the likely direction of future endeavors. After an introductory section describing the histological and anatomical features of the salivary glands and salivary function, salivary collection devices and diagnostic platforms are reviewed. The field of “salivaomics” is then considered in detail, covering, for example, proteomics, the peptidome, DNA and RNA analysis, biomarkers, and methods for biomarker discovery. Salivary diagnostics for oral and systemic diseases are thoroughly discussed, and the role of salivary gland tissue engineering for future diagnostics is explored. The book closes by considering legal issues and barriers to salivary diagnostic development. Advances in Salivary Diagnostics will be an informative and stimulating reference for both practitioners and students.
This book represents an unparalleled guide to the academic, scientific, clinical, and commercial applications of saliva as a diagnostic fluid.
Author: David T. Wong
Publisher: John Wiley & Sons
Salivary Diagnostics surveys one of the most exciting areas of research in oral biology. Regarded as the mirror of the body, saliva has immense potential to yield real clinical improvements in our ability to diagnose, and hence treat, oral and systemic conditions. The composition of saliva and other oral fluids reflects the tissue fluid levels of therapeutic, hormonal, and immunological molecules, as well as the presence of markers for systemic and oral disease.
This book provides information on biomarkers found in oral fluids relevant to oral and systemic diseases, with emphasis on salivary molecules and their potential to provide screening diagnosis for periodontal disease.
Author: Priyanka N.
Publisher: LAP Lambert Academic Publishing
This book provides information on biomarkers found in oral fluids relevant to oral and systemic diseases, with emphasis on salivary molecules and their potential to provide screening diagnosis for periodontal disease. The book will provide greater impact on clinician education in diagnostics, disease-risk and disease prevention through the public health sector before diagnostics will be integrated into routine clinical periodontal practice. Although challenges remain ahead, the use of saliva based oral fluid diagnostics appear promising for future application to diagnose periodontal diseases and to prognosticate periodontal treatment outcomes.
This book contains information for a diverse audience, including dentists, oral biologists, experimental biologists, molecular biologists, oncologists, radiologists, oral and maxillofacial surgeons, and otorhinolaryngologists.
Author: Işıl Adadan Güvenç
Publisher: BoD – Books on Demand
Saliva is a complex fluid that maintains oral health and has many physiological functions. It is a noninvasive diagnostic fluid as well. Lately, salivary diagnostics has proven its potential to reach clinical practice in the near future for the early detection, diagnosis, and monitoring of various diseases. Salivary Glands - New Approaches in Diagnostics and Treatment is a comprehensive reference, which brings together information on salivary secretion and its disorders, the novel salivary diagnostic methods for numerous diseases, and new techniques in the treatment of salivary diseases. This book contains information for a diverse audience, including dentists, oral biologists, experimental biologists, molecular biologists, oncologists, radiologists, oral and maxillofacial surgeons, and otorhinolaryngologists.
Abstract: Oral health is important not only due to the diseases emerging in the oral cavity but also due to the direct relation to systemic health.
Author: Nagihan Bostanci
Abstract: Oral health is important not only due to the diseases emerging in the oral cavity but also due to the direct relation to systemic health. Thus, early and accurate characterization of the oral health status is of utmost importance. There are several salivary biomarkers as candidates for gingivitis and periodontitis, which are major oral health threats, affecting the gums. These need to be verified and validated for their potential use as differentiators of health, gingivitis and periodontitis status, before they are translated to chair-side for diagnostics and personalized monitoring. We aimed to measure 10 candidates using high sensitivity ELISAs in a well-controlled cohort of 127 individuals from three groups: periodontitis (60), gingivitis (31) and healthy (36). The statistical approaches included univariate statistical tests, receiver operating characteristic curves (ROC) with the corresponding Area Under the Curve (AUC) and Classification and Regression Tree (CART) analysis. The main outcomes were that the combination of multiple biomarker assays, rather than the use of single ones, can offer a predictive accuracy of > 90% for gingivitis versus health groups; and 100% for periodontitis versus health and periodontitis versus gingivitis groups. Furthermore, ratios of biomarkers MMP-8, MMP-9 and TIMP-1 were also proven to be powerful differentiating values compared to the single biomarkers
This book presents a thorough knowledge of the functions and properties of saliva, its role in health and disease, and the diagnostic technologies available for the identification of saliva biomarkers.
Salivary. Acute. Phase. Proteins. as. Biomarker. in. Oral. and. Systemic. Disease. Assya. Krasteva. and. Angelina. Kisselova. Medical University, Sofia Bulgaria 1. Introduction The purpose of this review is to present the latest ...
Author: Francisco Veas
Publisher: BoD – Books on Demand
The two volumes of Acute Phase Proteins book consist of chapters that give a large panel of fundamental and applied knowledge on one of the major elements of the inflammatory process during the acute phase response, i.e., the acute phase proteins expression and functions that regulate homeostasis. We have organized this book in two volumes - the first volume, mainly containing chapters on structure, biology and functions of APP, the second volume discussing different uses of APP as diagnostic tools in human and veterinary medicine.
333 20.4 Salivary Biomarkers in Oral and Systemic Diseases 20 Salivary Biomarkers of Oxidative Stress Associated with Periodontal Diseases While there is no comprehensive definition of a biomarker, it can be defined as: “a biomarker is ...
Author: Daisuke Ekuni
Publisher: Springer Science & Business Media
The chapters of Studies on Periodontal Disease comprise four parts. Part 1 provides basic sciences from the general to the particular. The findings of cell culture and animal models supply the mechanism between periodontal disease and oxidative stress. In part 2, human clinical studies are mainly addressed. The effects of periodontal therapy on circulating oxidative stress are also discussed. The relationships between periodontal disease and systemic diseases are examined in part 3. The involvement of oxidative stress and inflammation are discussed through in vivo and in vitro study results. Part 4 discusses future strategies, including the effects of antioxidants and nutrition on periodontal disease. This thorough examination of the relationship between oxidative stress and periodontal disease is essential reading for researchers in oxidative stress and periodontal clinicians, alike.