The Telomerase Revolution

The Telomerase Revolution

The Telomerase Revolution is the definitive work on the latest science on human aging, covering both the theory and the clinical implications. It takes the reader to the forefront of the upcoming revolution in human medicine.

Author: Michael Fossel

Publisher: BenBella Books, Inc.

ISBN: 9781941631706

Category: Science

Page: 256

View: 831

One of Wall Street Journal’s "Best Books for Science Lovers" in 2015 Science is on the cusp of a revolutionary breakthrough. We now understand more about aging—and how to prevent and reverse it—than ever before. In recent years, our understanding of the nature of aging has grown exponentially, and dramatic life extension—even age reversal—has moved from science fiction to real possibility. Dr. Michael Fossel has been in the forefront of aging research for decades and is the author of the definitive textbook on human aging. In The Telomerase Revolution, he takes us on a detailed but highly accessible scientific journey, providing startling insights into the nature of human aging. Twenty years ago, there was still considerable debate of the nature of human aging, with a variety of competing theories in play. But scientific consensus is forming around the telomere theory of aging. The essence of this theory is that human aging is the result of cellular aging. Every time a cell reproduces, its telomeres (the tips of the chromosomes) shorten. With every shortening of the telomeres, the cell’s ability to repair its molecules decreases. It ages. Human aging is the result of the aging of the body’s trillions of cells. But some of our cells don’t age. Sex cells and stem cells can reproduce indefinitely, without aging, because they create telomerase. Telomerase re-lengthens the telomeres, keeping these cells young. The Telomerase Revolution describes how telomerase will soon be used as a powerful therapeutic tool, with the potential to dramatically extend life spans and even reverse human aging. Telomerase-based treatments are already available, and have shown early promise, but much more potent treatments will become available over the next decade. The Telomerase Revolution is the definitive work on the latest science on human aging, covering both the theory and the clinical implications. It takes the reader to the forefront of the upcoming revolution in human medicine.
Categories: Science

Chasing Methuselah

Chasing Methuselah

156 Her co-authored book entitled The Telomere Effect: A Revolutionary
Approach to Living Younger, Healthier, Longer (2017), joins a rapidly expanding
list of recent offerings with titles such as The Telomerase Revolution, The
Telomere ...

Author: Todd T. W. Daly

Publisher: Wipf and Stock Publishers

ISBN: 9781532698002

Category: Religion

Page: 324

View: 588

The quest to live much longer has moved from legend to the laboratory. Recent breakthroughs in genetics and pharmacology have put humanity on the precipice of slowing down human aging to extend the healthy life span. The promise of longer, healthier life is enormously attractive, and poses several challenging questions for Christians. Who wouldn’t want to live 120 years or more before dying quickly? How do we make sense of human aging in light of Jesus’ invitation to daily take up our crosses with the promise of the resurrection to come? Is there anything wrong with manipulating our bodies technologically to live longer? If so, how long is too long? Should aging itself be treated as a disease? In Chasing Methuselah, Todd Daly examines the modern biomedical anti-aging project from a Christian perspective, drawing on the ancient wisdom of the Desert Fathers, who believed that the incarnation opened a way for human life to regain the longevity of Adam and the biblical patriarchs through prayer and fasting. Daly balances these insights with the christological anthropology of Karl Barth, discussing the implications for human finitude, fear of death, and the use of anti-aging technology, weaving a path between outright condemnation and uncritical enthusiasm.
Categories: Religion

Aging is a Group Selected Adaptation

Aging is a Group Selected Adaptation

The Green Revolution [89,90] has increased grain yields per acre by five- or ten-
fold since the 19th century. ... Fossel, M., The Telomerase Revolution: The
Enzyme That Holds the Key to Human Aging... and Will Soon Lead to Longer,
Healthier ...

Author: Joshua Mitteldorf

Publisher: CRC Press

ISBN: 9781315354033

Category: Medical

Page: 243

View: 356

Although books exist on the evolution of aging, this is the first book written from the perspective of again as an adaptive program. It offers an insight into the implications of research on aging genetics, The author proposes the Demographic Theory of Senescence, whereby aging has been affirmatively selected because it levels the death rate over time helping stabilize population dynamics and prevent extinctions.
Categories: Medical

Annals of the Academy of Medicine Singapore

Annals of the Academy of Medicine  Singapore

They are ( 1 ) age and ageing , ( 2 ) alternative medicine , ( 3 ) AIDS , ( 4 ) the
human genome and ( 5 ) the information revolution . ( a ) The Telomere Story
One of the most exciting research in ageing has resulted from the genetic study of
a ...

Author: Academy of Medicine (Singapore)

Publisher:

ISBN: UCLA:L0088703616

Category:

Page:

View: 267

Categories:

In Vivo

In Vivo

3 Banks DA , Fossel M : Telomeres , cancer , and aging , altering the human
lifespan . JAMA 278 ... Vaziri H : Extension of Life Span in Normal Human Cells
by Telomerase Activation : A Revolution in Culhlral Senescence . Journal of Anti
 ...

Author:

Publisher:

ISBN: UCLA:L0090608001

Category:

Page:

View: 390

Categories:

Inhibition of Telomerase from Human Ovarian Cancer Cells Via the Stabalization of G quadruplex Structures by Various Chemotheraputic Agents

Inhibition of Telomerase from Human Ovarian Cancer Cells Via the Stabalization of G quadruplex Structures by Various Chemotheraputic Agents

I wanted to be a part of the scientific revolution that is still occurring every time
breakthroughs are made in understanding life ' s code . I hoped to have a positive
impact on that revolution . The machine of scientific discovery has its big gears ...

Author: Paul Edrick Schutt

Publisher:

ISBN: UOM:49015002777838

Category:

Page: 50

View: 222

Categories:

Russ Coile s Health Care Forecast

Russ Coile s Health Care Forecast

GenomOn the far side of the technology , new genetic discov ics offers the
possibility of treating the root ( genetic ) eries hold out the promise of “ anti - aging
" " The Quiet Genetics Revolution : treatments one day . Isolation of telomerase ...

Author: Russell C. Coile

Publisher:

ISBN: 0834218720

Category: Hospitals

Page: 106

View: 861

Categories: Hospitals

Men s Health the Hormone Revolution

Men s Health   the Hormone Revolution

Besides the telomerase enzyme and the chemical wear - and - tear caused by
free oxygen radicals , are there any other ... Recent research in the field of
endocrinology has provided us The Hormone Revolution 163 THE MALE
HORMONES ...

Author: Siegfried Meryn

Publisher: Richmond Hill, ON : NDE Pub.

ISBN: CORNELL:31924073880464

Category: Aging

Page: 318

View: 960

This controversial guide explores how aging affects a man's life & how hormones play a pivotal role in mental fitness, stress, mid-life crises, & virility.
Categories: Aging

New Scientist

New Scientist

And it was Geron that identified the gene for telomerase , the enzyme that
rebuilds the telomeres at the ends of ... prophet and wheeler" echo of the big
bang " in 1965 . things , that the universe is 13.7 billion dealer of the biotech
revolution .

Author:

Publisher:

ISBN: UCSD:31822022840573

Category: Science

Page:

View: 931

Categories: Science

The Journal of the Association of Physicians of India

The Journal of the Association of Physicians of India

... INAUGURATION HONOUR LECTURE Chairpersons Lekha Pathak / V
Parameshvara For whom the Telomerase Tolls ... How Effective and How Soon A
Seth ( New Delhi ) Minimally Invasive Cardiac Surgery : A Revolution in the
Making N ...

Author:

Publisher:

ISBN: UCLA:L0080472665

Category: Medicine

Page:

View: 257

Categories: Medicine

Visions

Visions

If we can neutralize telomerase , we can make the cells mortal again , just like
other cells . No one knows precisely which therapy will be most effective against
cancer . But the point is that the biomolecular revolution has now cracked the ...

Author: Michio Kaku

Publisher: Oxford University Press, USA

ISBN: UVA:X004218844

Category: Science

Page: 403

View: 840

In this text, physicist Michio Kaku looks to this future and guides the reader through the science of the next century. His vision of this future is based on the pioneering efforts by theoreticians and the current laboratory research. Dr Kaku asserts that, using today's knowledge, we can confidently predict the direction of science through the next century.
Categories: Science

Lung Cancer An Issue of Clinics in Chest Medicine E Book

Lung Cancer  An Issue of Clinics in Chest Medicine   E Book

Activation of telomerase (the telomere-lengthening enzyme required for cell
immortality) and disruption or escape from apoptotic pathways are other common
events in cancer cells. Over the past 5 to 10 years there has been a revolution in
 ...

Author: Lynn T. Tanoue

Publisher: Elsevier Health Sciences

ISBN: 9781455709717

Category: Medical

Page: 311

View: 532

Carcinoma of the lung is one of the most prevalent and aggressive types of cancer, and rates of lung cancer are on the rise. This issue gives a comprehensive review of the most recent advances in Lung Cancer. Epidemiology, etiology, and prevention of lung cancer is first discussed, followed by articles on pre-invasive evaluation and management, screening, pathology and molecular biology. There is an article on the approach to the ground glass nodule. Of great importance is the revised staging classification of Lung Cancer, which is discussed here in detail. Articles on PET imaging, interventional pulmonary, and functional evaluation before Lung Resection are also included. The issue then focuses on advances in treatment for early stage lung cancer, high risk patients with early stage lung cancer, advances in the treatment of Advanced Stage Lung Cancer, Small Cell Lung Cancer, and gene therapy for lung neoplasms.
Categories: Medical

The Personalized Medicine Revolution

The Personalized Medicine Revolution

The Personalized Medicine Revolution explores recent advances in genomics, the study of the human genome ? as well as its cousins proteomics, metabolomics, microbiomics, and the like ? and explains how technology is even now changing the ...

Author: Pieter Cullis

Publisher: Greystone Books Ltd

ISBN: 9781771640381

Category: Health & Fitness

Page: 176

View: 448

Every year more than 2 million North Americans are hospitalized, and more than 100,000 lose their lives, because of adverse reactions to drugs. These tragic cases stem from our one-size-fits-all approach to medicine. But who we are-our age, our sex, our size, our ethnic heritage-matters to our health. Shouldn't our medicine be tailored to our differences? Through the stories of researchers, scientists, and patients, The Personalized Medicine Revolution explores the promising new advances in personalized medicine-healthcare based on each person's unique genetic and molecular makeup-and the coming sea change in the way we detect and treat disease. The book also discusses the issues that patients, researchers, and governments will face as we take the next steps into this exciting future and explains what readers can do to take charge of their health.
Categories: Health & Fitness

Liberation Biology

Liberation Biology

The Scientific and Moral Case for the Biotech Revolution Ronald Bailey. gives
them a big jolt of telomerase . ” 34 The dendritic cells , which now display the
telomerase protein , are injected back into a patient as a vaccine . Like all
vaccines ...

Author: Ronald Bailey

Publisher:

ISBN: UOM:39015061445949

Category: Science

Page: 332

View: 187

An examination of the future of biology and what it will mean for humanity looks at the possibilities that recent scientific advances have made possible and discusses the ethical implications of the sciences of the future.
Categories: Science

The next genesis

The next genesis

“All right, I can understand this. Perhaps we will also train our adult population
with Prosis, allowing them to also participate in your revolution. They have the
experience we need. I can make no guarantees, but I will recommend it to the
Prince.

Author: Kimberly Coghlin

Publisher: Transmedia Press

ISBN: 9781935805533

Category: Liberty

Page: 472

View: 179

Categories: Liberty

Genetics Abstracts

Genetics Abstracts

Accelerated telomere loss has been proposed to be a factor leading to end -
stage organ failure in chronic diseases of high ... The new genetics , emerging as
a scientific revolution , is reinforcing the biological theories which accounts for ...

Author:

Publisher:

ISBN: UOM:39015050439754

Category: Genetics

Page:

View: 226

Categories: Genetics

Interorganellar Signaling in Age Related Disease

Interorganellar Signaling in Age Related Disease

Author: M.P. Mattson

Publisher: Elsevier Science Limited

ISBN: UOM:39015060825760

Category: Medical

Page: 272

View: 735

Collectively, the chapters in this work will provide the reader with novel insight into the inter-relationships of the function of different organelles in the sequences of events that lead to cellular dysfunction and degeneration in the aging human population. The chapters are rich in information for cell and molecular biologists pursuing studies of the different diseases covered. In addition, the clinician will find value in understanding mechanisms underlying age-related disease as such an understanding will lead to novel therapeutic approaches for an array of age-related diseases.
Categories: Medical