For a long time, immunology has been dominated by the idea of a simple linear cause-effect relationship between the exposure to an antigen and the production of specific antibodies against that antigen.
Author: Henri Atlan
Publisher: Springer Science & Business Media
For a long time, immunology has been dominated by the idea of a simple linear cause-effect relationship between the exposure to an antigen and the production of specific antibodies against that antigen. Clonal selection was the name of the theory based on this idea and it has provided the main concepts to account for the known features of the immune response. More recently, immunologists have discovered a wealth of new facts, in the form of different regulatory cells (helpers, suppressors, antigen presenting cells), genetic determinations of immune responses such as those involved in graft re jections, different molecular structures responsible for intercellular interactions such as interleukins, cytokins, idiotype-antiidiotype recognition and others. While furthering our understanding of the local interactions (molecular and cellular) in volved in the immune response, these discoveries have led to a questioning of the simplicities of the classical clonal selection theory. It is clear today that every single immune response is a cooperative phenomenon involving several different molecular and cellular interactions taking place in a coupled manner. In addition, cross reactivity to different antigens has shown that responses of the whole im mune system to different antigens are not completely isolated from one another and that the history of encounters with different antigens plays a crucial role in the maturation of the whole system. Thus, problems of complexity, generation of di versity and self-organization have entered the field of immunology.
( 4 ) H. Atlan , and I.R. Cohen , eds . , Theories of Immune Networks , Springer -
Verlag , Berlin , 1989 . ( 5 ) A.S. Perelson , “ Immune network theory ” , Immunol .
ogy Review , no . 10 , pp . 5-36 , 1989 . ( 6 ) T. Ikegami , “ Dynamical behavior of ...
Proceedings of the May 1997 symposium. MVL researchers from around the world present 37 papers in sessions on algebra, device technology, circuits, fuzzy logic, logic design, philosophical aspects, spectral techniques, testing and fault simulation, and applications. In addition, three invited addresses--recent developments in DNA- computing; many-valuedness and uncertainty; and ternary decision diagrams (survey)--further illustrate the diverse nature of multiple-valued research. Topics of the papers include finding composition trees for multiple-valued functions; hyperclones on a finite set; and multiple-valued logic as a programming language. No index. Annotation copyrighted by Book News, Inc., Portland, OR.
Author: National Library of Medicine (U.S.)Publish On:
9012740 Theories of immune networks / H. Atlan , I.R. Cohen ( eds . ) ... Immune
System - physiology - congresses 2 . ... 9010244 Theory and practice of
histological techniques / edited by John D. Bancroft , Alan Stevens ; foreword by
Author: National Library of Medicine (U.S.)
First multi-year cumulation covers six years: 1965-70.
( 23 ) N. K. Jerne , “ The Immune System , ” Sci . Am . , 1 ( 1973 ) 52-60 . [ 24 ] Z.
Grossman , “ The Concept of Idiotypic Network : Deficient or Premature ? " in Theories of Immune Networks , edited by H. Atlan and I. R. Cohen ( Springer -
Author: Leandro Nunes CastroPublish On: 2002-09-23
Atlan, H. & Cohen, I. R. (1989), Theories of Immune Networks, Springer- Verlag.
Bernardes, A. T. & dos Santos, R. M. Z. (1997), "Immune Network at the Edge of
Chaos", / theor. Biol, 186, pp. 173-187. Bersini, H. & Calenbuhr, V. (1997), ...
Author: Leandro Nunes Castro
Publisher: Springer Science & Business Media
Recently there has been a growing interest in the use of the biological immune system as a source of inspiration for solving complicated computational problems. The immune system involves many information-processing abilities including pattern recognition, learning, memory and inherent distributed parallel processing and for these, and other reasons, it has received a significant amount of interest as a metaphor within computing. This emerging field is known as Artificial Immune Systems (AIS), and applications of AIS include, machine learning, fault diagnosis, computer security, scheduling, virus detection and optimisation.
TRADITIONAL THEORIES OF IMMUNITY According to traditional immunology,
specific humoral immunity is based on a classical ... Network Theory Perelson (
32) described immune network theory as a system providing for both stability and
Author: Robert A. Leach
Publisher: Lippincott Williams & Wilkins
Designed to be a primary reference for chiropractic students, this is a concise, scientific survey of chiropractic theories based on current research. Completely restructured for the Fourth Edition, this book focuses on the most current biomedical research on the three phase model of vertebral subluxation complex (V.S.C.). This is a useful reference for students studying for the National Board of Chiropractors Examination Parts II, III, and IV, as well as a post-graduate reference providing information on the chiropractic perspective on health and wellness, nutrition, exercise, psychosocial issues, and case management principles for wellness care. This new text focuses on developing critical thinking among chiropractic students, and includes new contributors and new chapters on principles of statistics and a minimum process for validation of chiropractic theory.
... I . R . ( 1989 ) Natural id - anti - id networks and the immunological homunculus
, in : Theories of Immune Networks , eds . Atlan , H . and Cohen , I . R . , Springer
Verlag , Heidelberg Paul W . E . ( 1989 ) The immune system : An introduction ...
Introduction The vertebrate immune system has several useful mechanisms from
the viewpoint of of information processing . Among the many immunological
models , we can stress the immune network theory [ 6 ] and the clonal selection
Author: Carlos H. C. Ribeiro
With 46 papers from the November 2000 conference in Rio de Janeiro, this volume represents the work of computer scientists, artificial intelligence researchers, and engineers from around the world. They address issues like neurosymbolic processing, neural computation, scalars, CDMA and TCMA based neural nets, genetic algorithms, PARMA modeling, hierarchical neural models, web text mining, inverse kinematics problems in robot control, image compression, and morphological rules of similarity. Also included are abstracts of 24 other papers, originally written in Portugese or Spanish. Name index only. Annotation copyrighted by Book News, Inc., Portland, OR.
A network theory of the immune system. Eur. J. Immunol. 5, 350–354. Richter,
P. H. (1978). The network idea and the immune response. In: Theoretical
Immunology, eds., G. I. Bell, A. S. Perelson and G. H. Pimbley, Jr., Marcel Dekker,
Author: Andersson Stig I
Publisher: World Scientific
For the mathematical modeling of complex system behavior, dynamical systems play an increasing role. The flexibility and very rich phenomenology exhibited by such systems make them indispensible in this context. Control theory for dynamical systems is also a highly active field of research where a number of important results have been achieved recently.This combined course and workshop deals with recent results regarding dynamical systems and control theory, primarily in differential geometric terms as well as the applications of these fields to biological systems, with an emphasis on various aspects of the immune system and on neural networks.
C - 21 1197 – 206 [ 12 ] Kauffman S 1971 Gene regulation networks : theory for
their global structure and behaviors ... of the immune cellular response by small
neural networks Theories of the Immune Networks ed H Atlan and I R Cohen ...
262 Book Review H . ATLAN , I . R . COHEN ( Eds . ) : Theories of Immune Networks Springer - Verlag Berlin Heidelberg New York 117 Pages , 23 Figures ,
Format 17 cm x 24 cm price : DM 85 , - - The fact that the immunological reaction
of a ...
Variability in spike trains during constant and dynamic stimulation . Science 283 ,
1927–1930 . Weisbuch , G. ( 1989 ) . Dynamical behavior of discrete models of
Jerne's network . In H. Atlan and I. Cohen ( Eds . ) , Theories of Immune Networks
to immune network theory . In Theoretical Immunology , Part Two ( ed . A . S .
Perelson ) , pp . 321 - 43 . Addison - Wesley , Redwood City , CA . Segel , L . A .
and Perelson , A . S . ( 1989a ) A paradoxical instability caused by relatively short
Author: A. Goldbeter
Category: Cell interaction
"These papers were first presented at the NATO Advanced Research Workshop 'Theoretical Models for Cell to Cell Signalling' held in Knokke-Zoute, Belgium, during September 1988. The Workshop was further supported by the Commission of the European Communities."--Preliminary page.
Author: Professor of Philosophy Emeritus Zoltan Kohn Professor Emeritus of Medicine Alfred I TauberPublish On: 1997
The Concept of Idiotypic Network : Deficient or Premature ? In Theories of Immune Networks , ed . H . Atlan and I . R . Cohen , 38 – 52 . Berlin :
SpringerVerlag . - 1993 . Cellular Tolerance as a Dynamic State of the Adaptable
Author: Professor of Philosophy Emeritus Zoltan Kohn Professor Emeritus of Medicine Alfred I Tauber
In recent decades immunology has been one of the most exciting--and successful--fields of biomedical research. Over the past thirty years immunologists have acquired a detailed understanding of the immune system's unique recognition mechanism and of the cellular and chemical means used to destroy or neutralize invading organisms. This understanding has been formulated in terms of the clonal selection theory, the dominant explanation of immune behavior. That story is the subject of The Generation of Diversity. A major problem for immunologists had long been to determine how cells of the immune system could produce millions of distinct antibodies--and produce them on demand. The clonal selection theory explains that cells with genetic instructions to produce each antibody exist in the body in small numbers until exposure to the right molecule--the antigen--triggers the selective cloning that will reproduce exactly the cell needed. But how can so many different antibody-producing cells be generated from such limited genetic material? The solution to this question came from new applications of molecular biology, and, as the authors argue, the impact of the new techniques changed both the methods and the concepts of immunology. The Generation of Diversity is an intellectual history of the major theoretical problem in immunology and its resolution in the post-World War II period. It will provide for immunologists essential background for understanding the conceptual conflicts occurring in the field today.
Network Regulation of Autoimmunity : An Automaton Model . J . Autoimmunity , 2
, 1989 , pp . 613 - 625 . 15 ) H . Atlan and S . H . Snyder . Simulation of the Immune Cellular Response by Small Neural Networks , in : Theories of Immune ...
Author: C. Rossi
Publisher: Elsevier Science Limited
Category: Technology & Engineering
A great debate has arisen about the necessity to distinguish between different physical chemistry approaches for investigating the behavior of natural systems. On the one side, it is necessary to recognize that the use of time-reversible classical and quantum physical chemistry approaches for studying molecular systems yields a big improvement in man's knowledge. On the other hand it is imperative to have new approaches, new time-irreversible theories, able to describe these relationships. Ecological physical chemistry is a new transdisciplinary field of study that addresses the relationships between complex molecular systems and/or organisms. This new field goes beyond the normal conceptions of scientific disciplines and tries to integrate and harmonize many different disciplinary perspectives. Ecological physical chemistry thus, wants to develop new theories and strategies for investigating the complexity of nature, and the present book is the first report on this intriguing new scientific discipline.
NETWORK INTERACTIONS IN THE GENERATION OF THE T - HELPER CELL
REPERTOIRE We will start by assuming ... low affinity interactions with self that is
so often involved in theories dealing with the generation of the T - cell repertoire .
Multi - level Selection and Immune Networks : Preliminary Discussion of an
Abstract Model Tom Lenaerts , Anne ... is the number of ways of the immune network theory proposed inability of artificial models to construct functional hier
by N . K ...
Category: Biological systems
Consists of the proceedings of: 1987, Interdisciplinary Workshop on the Synthesis and Simulation of Living Systems; 1990-1992, Artificial Life Workshop; 1994-1996, International Workshop on the Synthesis and Simulation of Living Systems; 1998- , International Conference on Artificial Life.
IMMUNITY-IMPATIENS IMPEACHMENT IMPEACHMENT IMPEACHMENT TEXT
OF THE REPORT BY THE U. 816 ALLERGIES When an antigen and ... Theories of Immune Networks (Sprlnger-VerUR 1989). Brehelin, M., ed.. Immunity in ...